Literature DB >> 3319254

[New focus of chloroquine-resistant malaria in a forestry zone in Cameroon].

J Kouamouo1, P Enyong, P Brasseur, S R Moyou, P Druilhe.   

Abstract

In vitro sensitivity of P. falciparum to chloroquine and quinine was studied in Hevecam rubber plantations of la Nyete in Cameroon, located at 45 km in the south east of Kribi in a forest area. More than half of the isolates studied (14/25) were resistant to chloroquine (EC50 greater than 80 nmole/l). The mean EC50 and EC99 were 113 nmole/l and 4,110 nmole/l respectively. The sensitivity to quinine was decreased, as compared to other area of the country. Kribi is the third area of chloroquine-resistance known in Cameroon.

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Year:  1987        PMID: 3319254

Source DB:  PubMed          Journal:  Bull Soc Pathol Exot Filiales


  1 in total

1.  Prolonged malaria prophylaxis with chloroquine and proguanil (chloroguanide) in a nonimmune resident population of an endemic area with a high prevalence of chloroquine resistance.

Authors:  D Gozal; C Hengy; G Fadat
Journal:  Antimicrob Agents Chemother       Date:  1991-02       Impact factor: 5.191

  1 in total

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