Literature DB >> 3318846

Localization of Ro (SS-A) antigen in the cardiac conduction system.

J S Deng1, L W Bair, S Shen-Schwarz, R Ramsey-Goldman, T Medsger.   

Abstract

The presence of anti-Ro (SS-A) antibody in maternal serum has been associated with congenital heart block. Using human sera monospecific for anti-Ro (SS-A) antibodies in an indirect immunofluorescence assay, Ro (SS-A) antigen was found to be present in the nuclei of myocardial cells and cells of the cardiac conduction system. The possible relationship between the location of Ro (SS-A) antigen, anti-Ro (SS-A) antibody, and heart block is discussed.

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Year:  1987        PMID: 3318846     DOI: 10.1002/art.1780301105

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  11 in total

1.  Neonatal lupus erythematosus associated with unilateral pectoralis major atrophy.

Authors:  Rakesh Mondal; Madhumita Nandi; Sumantra Sarkar; Krishnendu Mukherjee
Journal:  Indian J Pediatr       Date:  2011-05-08       Impact factor: 1.967

2.  Possible association between anti-Ro antibodies and myocarditis or cardiac conduction defects in adults with systemic lupus erythematosus.

Authors:  D Logar; T Kveder; B Rozman; J Dobovisek
Journal:  Ann Rheum Dis       Date:  1990-08       Impact factor: 19.103

Review 3.  Anti-Ro(SSA) and anti-La(SSB) antibodies in autoimmune rheumatic diseases.

Authors:  P Youinou; Y Adler; S Muller; A Lamour; D Baron; R L Humbel
Journal:  Clin Rev Allergy       Date:  1994

4.  Variable atrioventricular block in systemic lupus erythematosus.

Authors:  Sybille Liautaud; Ahmed J Khan; Shireesha R Nalamasu; Irene J Tan; Anekwe E Onwuanyi
Journal:  Clin Rheumatol       Date:  2004-10-26       Impact factor: 2.980

Review 5.  Pathogenesis of SLE: immunopathology in man.

Authors:  J R Kalden; T H Winkler; M Herrmann; F Krapf
Journal:  Rheumatol Int       Date:  1991       Impact factor: 2.631

6.  Investigations into Ro-specific antibody-associated congenital cardiac conduction defects.

Authors:  T Dörner; F Hiepe; B Göldner; E Apostoloff
Journal:  Clin Investig       Date:  1992-06

7.  Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus.

Authors:  J P Buyon; E Ben-Chetrit; S Karp; R A Roubey; L Pompeo; W H Reeves; E M Tan; R Winchester
Journal:  J Clin Invest       Date:  1989-08       Impact factor: 14.808

8.  The human Y4 small cytoplasmic RNA gene is controlled by upstream elements and resides on chromosome 7 with all other hY scRNA genes.

Authors:  R J Maraia; N Sasaki-Tozawa; C T Driscoll; E D Green; G J Darlington
Journal:  Nucleic Acids Res       Date:  1994-08-11       Impact factor: 16.971

Review 9.  Clinical and pathological roles of Ro/SSA autoantibody system.

Authors:  Ryusuke Yoshimi; Atsuhisa Ueda; Keiko Ozato; Yoshiaki Ishigatsubo
Journal:  Clin Dev Immunol       Date:  2012-12-06

10.  Immune-mediated axonal dysfunction in seropositive and seronegative primary Sjögren's syndrome.

Authors:  Jowy Tani; Hsien-Tzung Liao; Hui-Ching Hsu; Lung-Fang Chen; Tsui-San Chang; Cindy Shin-Yi Lin; Jia-Ying Sung
Journal:  Ann Clin Transl Neurol       Date:  2020-05-15       Impact factor: 4.511

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