Literature DB >> 33187549

Correction to: Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex.

Kohei Koga1,2,3, Akihiro Yamada3, Qian Song1,2, Xu-Hui Li1,2, Qi-Yu Chen1,2, Ren-Hao Liu1, Jun Ge4, Cheng Zhan5,6, Hidemasa Furue3, Min Zhuo7,8, Tao Chen9,10.   

Abstract

An amendment to this paper has been published and can be accessed via the original article.

Entities:  

Year:  2020        PMID: 33187549      PMCID: PMC7664103          DOI: 10.1186/s13041-020-00692-4

Source DB:  PubMed          Journal:  Mol Brain        ISSN: 1756-6606            Impact factor:   4.041


Correction to: Molecular Brain (2020) 13:49 10.1186/s13041-020-00586-5

Following publication of the original article [1], the authors identified an error in Fig. 3: repeated figures were used in Fig. 3a (lower panel) and Fig. 3b (middle panel). To correct this, the original Fig. 3a (lower panel) was replaced with a new sample figure. The correct complete Fig. 3 and its caption are given below and the original article has been corrected.
Fig. 3

Noradrenaline induced inward current in pyramidal cells via α1 receptor. a Samples showing High dose (50 μM) but not low dose (10 μM) of NA produced inward currents. b Samples showing α1 receptors antagonist prazosin, but not α2 receptors antagonist yohimbine nor β1 receptors antagonist propranolol blocked the inward current induced by NA (50 μM). c Averaged results showing high dose but not low dose of NA induced inward current (10 μM NA: n = 13, 50 μM NA: n = 12, 100 μM NA: n = 12). The inward currents were blocked by α1 receptors antagonist, but not α2 receptors nor β receptors antagonist. High dose of NA (50 μM) produced inward current is blocked by Prazosin (10 μM NA: 0.34 ± 3.74 pA, n = 13; 50 μM NA: 23.73 ± 4.13 pA, n = 12; 100 μM NA: 15.69 pA ± 3.82 pA, n = 12; Prazosin:: − 5.94 ± 3.76 pA, n = 9; Yohimbine: 20.58 ± 4.59 pA, n = 8; Propranolol: 16.35 ± 4.79 pA, n = 8). *P < 0.05, 10 μM NA vs. 50 μM or 100 μM NA, Prazosin vs. Yohimbine or Propranolol. One-Way ANOVA

Noradrenaline induced inward current in pyramidal cells via α1 receptor. a Samples showing High dose (50 μM) but not low dose (10 μM) of NA produced inward currents. b Samples showing α1 receptors antagonist prazosin, but not α2 receptors antagonist yohimbine nor β1 receptors antagonist propranolol blocked the inward current induced by NA (50 μM). c Averaged results showing high dose but not low dose of NA induced inward current (10 μM NA: n = 13, 50 μM NA: n = 12, 100 μM NA: n = 12). The inward currents were blocked by α1 receptors antagonist, but not α2 receptors nor β receptors antagonist. High dose of NA (50 μM) produced inward current is blocked by Prazosin (10 μM NA: 0.34 ± 3.74 pA, n = 13; 50 μM NA: 23.73 ± 4.13 pA, n = 12; 100 μM NA: 15.69 pA ± 3.82 pA, n = 12; Prazosin:: − 5.94 ± 3.76 pA, n = 9; Yohimbine: 20.58 ± 4.59 pA, n = 8; Propranolol: 16.35 ± 4.79 pA, n = 8). *P < 0.05, 10 μM NA vs. 50 μM or 100 μM NA, Prazosin vs. Yohimbine or Propranolol. One-Way ANOVA
  1 in total

1.  Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex.

Authors:  Kohei Koga; Akihiro Yamada; Qian Song; Xu-Hui Li; Qi-Yu Chen; Ren-Hao Liu; Jun Ge; Cheng Zhan; Hidemasa Furue; Min Zhuo; Tao Chen
Journal:  Mol Brain       Date:  2020-03-26       Impact factor: 4.041

  1 in total

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