Havva Kocayiğit1, Kezban Özmen Süner2, Yakup Tomak3, Gürkan Demir3, İbrahim Kocayiğit4, Selçuk Yaylacı5, Yusuf Aydemir6, Mehmet Köroğlu7, Oğuz Karabay8, Mehmet Halil Öztürk9, Ali Fuat Erdem3. 1. Department of Anaesthesiology and Reanimation, Sakarya University Education and Research Hospital, Sakarya, Turkey 2. Department of Intensive Care, Sakarya University Education and Research Hospital, Sakarya, Turkey 3. Department of Anaesthesiology and Reanimation, Faculty of Medicine, Sakarya University, Sakarya, Turkey 4. Department of Cardiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey 5. Department of Internal Medicine, Faculty of Medicine, Sakarya University, Sakarya, Turkey 6. Department of Pulmonary Diseases, Faculty of Medicine, Sakarya University, Sakarya, Turkey 7. Department of Medical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey 8. Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey 9. Department of Radiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey
Abstract
Background/aim: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Turkey on March 10, 2020 and the number of the patients are increasing day by day. Coronavirus disease 2019 (Covid-19) has high mortality rates in intensive care units (ICUs). We aimed to describe the demographic characteristics, comorbidities, treatment protocols, and clinical outcomes among the critically ill patients admitted to the ICU of our hospital. Materials and methods: This cohort study included 103 consecutive patients who had laboratory confirmed Covid-19 and admitted to ICU of Sakarya University Training and Research Hospital between March 19 and April 13, 2020. The final date of the follow-up was April 18. Results: The mean age of the patients was 69.6 ± 14.1 years. Most of the patients had increased CRP (99%), serum ferritin (73.8%), d-dimer (82.5%), and hs-troponin levels (38.8%). 34 patients (33%) had lymphocytopenia, 24 patients (23.3%) had thrombocytopenia. 63 patients (61.2%) developed acute respiratory distress syndrome (ARDS), 31 patients (30.1%) had acute kidney injury, and 52 patients (50.5%) had multiple organ dysfunction syndrome (MODS) during follow-up. Sixty-two patients (60.2%) received mechanical ventilation. As of April 18, of the 103 patients, 52 (50.5%) had died, 30 (29.1%) had been discharged from the ICU, 21 (20.4%) were still in the ICU. Conclusions: Covid-19 has high mortality rates in ICU. Patients with elevated procalcitonin, hs-troponin, d-dimer, and CRP levels and lower platelet count at admission have higher mortality. This work is licensed under a Creative Commons Attribution 4.0 International License.
Background/aim: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Turkey on March 10, 2020 and the number of the patients are increasing day by day. Coronavirus disease 2019 (Covid-19) has high mortality rates in intensive care units (ICUs). We aimed to describe the demographic characteristics, comorbidities, treatment protocols, and clinical outcomes among the critically illpatients admitted to the ICU of our hospital. Materials and methods: This cohort study included 103 consecutive patients who had laboratory confirmed Covid-19 and admitted to ICU of Sakarya University Training and Research Hospital between March 19 and April 13, 2020. The final date of the follow-up was April 18. Results: The mean age of the patients was 69.6 ± 14.1 years. Most of the patients had increased CRP (99%), serum ferritin (73.8%), d-dimer (82.5%), and hs-troponin levels (38.8%). 34 patients (33%) had lymphocytopenia, 24 patients (23.3%) had thrombocytopenia. 63 patients (61.2%) developed acute respiratory distress syndrome (ARDS), 31 patients (30.1%) had acute kidney injury, and 52 patients (50.5%) had multiple organ dysfunction syndrome (MODS) during follow-up. Sixty-two patients (60.2%) received mechanical ventilation. As of April 18, of the 103 patients, 52 (50.5%) had died, 30 (29.1%) had been discharged from the ICU, 21 (20.4%) were still in the ICU. Conclusions: Covid-19 has high mortality rates in ICU. Patients with elevated procalcitonin, hs-troponin, d-dimer, and CRP levels and lower platelet count at admission have higher mortality. This work is licensed under a Creative Commons Attribution 4.0 International License.
Entities:
Keywords:
intensive care unit; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); coronavirus disease 2019 (Covid-19)
Authors: Pavan K Bhatraju; Bijan J Ghassemieh; Michelle Nichols; Richard Kim; Keith R Jerome; Arun K Nalla; Alexander L Greninger; Sudhakar Pipavath; Mark M Wurfel; Laura Evans; Patricia A Kritek; T Eoin West; Andrew Luks; Anthony Gerbino; Chris R Dale; Jason D Goldman; Shane O'Mahony; Carmen Mikacenic Journal: N Engl J Med Date: 2020-03-30 Impact factor: 91.245
Authors: Muhammed Elhadi; Ahmed Alsoufi; Abdurraouf Abusalama; Akram Alkaseek; Saedah Abdeewi; Mohammed Yahya; Alsnosy Mohammed; Mohammed Abdelkabir; Mohammed Huwaysh; Emad Amkhatirah; Kamel Alshorbaji; Samer Khel; Marwa Gamra; Abdulmueti Alhadi; Taha Abubaker; Mohamed Anaiba; Mohammed Elmugassabi; Muhannud Binnawara; Ala Khaled; Ahmed Zaid; Ahmed Msherghi Journal: PLoS One Date: 2021-04-30 Impact factor: 3.240