| Literature DB >> 33183189 |
Li Gao1, Min Cao1, Jia-Qi Li1, Xue-Mei Qin1, Jian-Song Fang2.
Abstract
Cardiovascular disease is a major disease affecting human health, and its pathogenesis is caused by many factors. Through the use of 'omics' technology, precision medicine is playing an increasingly important role in the prevention and treatment of cardiovascular diseases. Dialectical treatment with traditional Chinese medicine (TCM）will result in personalized treatment, which is consistent with precision medicine to a certain extent. However, due to the multitarget, multipath, and multistep characteristics of TCM, its mechanism of action is not easy to elucidate. Network pharmacology can be used to predict the mechanism, toxicity and metabolic characteristics of TCM. This review summarizes commonly used bioinformatics resources for cardiovascular diseases and TCM, as well as the opportunities and challenges of TCM in cardiovascular precision medicine, with special emphasis on network pharmacology methods. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: cardiovascular disease; metabolomics; network pharmacology; omics; precision medicine; traditional Chinese medicine; transcriptome
Year: 2020 PMID： 33183189 DOI： 10.2174/1381612826666201112142408
Source DB: PubMed Journal: Curr Pharm Des ISSN： 1381-6128 Impact factor: 3.116