Literature DB >> 3318131

[Participation of the proteolysis system in promoting the virulence of the influenza virus and development of the infectious process; the antiviral effect of protease inhibitors].

V P Lozitskiĭ, A S Fedchuk, L E Puzis, V P Buĭko, Iu I Girlia.   

Abstract

The results of the authors' own studies and data from the literature attesting to an important role of proteolytic mechanisms in influenza virus physiology and the development of the infectious process are summarized. The etiotropic and pathogenetic effectiveness of proteolysis inhibitors in influenza was demonstrated experimentally and clinically. Data are presented on the immunostimulating and prophylactic effect of a proteolysis inhibitor, E-aminocaproic acid. It is concluded that the use of proteolysis inhibitors in viral infections holds good promise.

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Year:  1987        PMID: 3318131

Source DB:  PubMed          Journal:  Vopr Virusol        ISSN: 0507-4088


  2 in total

1.  A high capacity microbial screen for inhibitors of human rhinovirus protease 3C.

Authors:  J O McCall; S Kadam; L Katz
Journal:  Biotechnology (N Y)       Date:  1994-10

Review 2.  Could Probiotics and Postbiotics Function as "Silver Bullet" in the Post-COVID-19 Era?

Authors:  Svetoslav Dimitrov Todorov; John Robert Tagg; Iskra Vitanova Ivanova
Journal:  Probiotics Antimicrob Proteins       Date:  2021-08-13       Impact factor: 4.609

  2 in total

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