Literature DB >> 33176392

Dosage of oxytocin for augmentation of labor and women's childbirth experiences: A randomized controlled trial.

Lotta Selin1,2, Marie Berg1,3, Ulla-Britt Wennerholm3,4, Anna Dencker1,5.   

Abstract

INTRODUCTION: The aim of this study was to compare childbirth experiences and experience of labor pain in primiparous women who had received high- vs low-dose oxytocin for augmentation of delayed labor.
MATERIAL AND METHODS: A multicenter, parallel, double-blind randomized controlled trial took place in six Swedish labor wards. Inclusion criteria were healthy primiparous women at term with uncomplicated singleton pregnancies, cephalic fetal presentation, spontaneous onset of labor, confirmed delayed labor progress and ruptured membranes. The randomized controlled trial compared high- vs low-dose oxytocin used for augmentation of a delayed labor progress. The Childbirth Experience Questionnaire version 2 (CEQ2) was sent to the women 1 month after birth. The CEQ2 consists of 22 items in four domains: Own capacity, Perceived safety, Professional support and Participation. In addition, labor pain was reported with a visual analog scale (VAS) 2 hours postpartum and 1 month after birth. The main outcome was the childbirth experience measured with the four domains of the CEQ2. The clinical trial number is NCT01587625.
RESULTS: The CEQ2 was sent to 1203 women, and a total of 1008 women (83.8%) answered the questionnaire. The four domains of childbirth experience were scored similarly in the high- and low-dose oxytocin groups of women: Own capacity (P = .36), Perceived safety (P = .44), Professional support (P = .84), Participation (P = .49). VAS scores of labor pain were reported as similar in both oxytocin dosage groups. Labor pain was scored higher 1 month after birth compared with 2 hours postpartum. There was an association between childbirth experiences and mode of birth in both the high- and low-dose oxytocin groups.
CONCLUSIONS: Different dosage of oxytocin for augmentation of delayed labor did not affect women's childbirth experiences assessed through CEQ2 1 month after birth, or pain assessment 2 hours or 1 month after birth.
© 2020 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).

Entities:  

Keywords:  birth; childbirth experience; delayed labor; labor pain; oxytocin augmentation; randomized controlled trial

Mesh:

Substances:

Year:  2021        PMID: 33176392     DOI: 10.1111/aogs.14042

Source DB:  PubMed          Journal:  Acta Obstet Gynecol Scand        ISSN: 0001-6349            Impact factor:   3.636


  3 in total

1.  Spontaneous Perineal Trauma during Non-Operative Childbirth-Retrospective Analysis of Perineal Laceration Risk Factors.

Authors:  Grażyna Bączek; Ewa Rzońca; Dorota Sys; Sylwia Rychlewicz; Anna Durka; Patryk Rzońca; Agnieszka Bień
Journal:  Int J Environ Res Public Health       Date:  2022-06-23       Impact factor: 4.614

2.  Maternal childbirth experience and pain relief methods: a retrospective 7-year cohort study of 85 488 parturients in Finland.

Authors:  Johanna Joensuu; Hannu Saarijärvi; Hanna Rouhe; Mika Gissler; Veli-Matti Ulander; Seppo Heinonen; Paulus Torkki; Tomi Mikkola
Journal:  BMJ Open       Date:  2022-05-09       Impact factor: 3.006

Review 3.  Oxytocin in Women's Health and Disease.

Authors:  Ning Liu; Haipeng Yang; Liqun Han; Mingxing Ma
Journal:  Front Endocrinol (Lausanne)       Date:  2022-02-15       Impact factor: 5.555

  3 in total

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