Literature DB >> 33174080

Benefit-Risk or Risk-Benefit Trade-Offs? Another Look at Attribute Ordering Effects in a Pilot Choice Experiment.

Sebastian Heidenreich1, Andrea Phillips-Beyer2, Bruno Flamion3, Melissa Ross1, Jaein Seo1, Kevin Marsh1.   

Abstract

BACKGROUND: Studies recommend randomising the order of attributes in discrete choice experiments (DCEs) to avoid bias; however, in a benefit-risk setting, this may increase the cognitive burden of respondents who compare the benefits and risks of treatments, or may affect their decision-making process. Based on these concerns, this paper explored attribute ordering effects in a benefit-risk DCE. <br> METHOD: Attribute ordering effects were explored in a large pilot DCE relating to the medical treatment of insomnia. Participants were randomised to one of three presentation orders: (1) benefits were presented before risks (BR); (2) risks were presented before benefits (RB); (3) all attributes were randomised (RN). For the RB and BR presentation orders, attributes were randomised within benefits and risks. Responses were assessed in three ways. First, variations in respondents' self-reported choice certainty were obtained. Second, variations in failure rates of stability and dominance tests were calculated. Third, a heteroscedastic error component model tested for differences in choice consistency across the three attribute orderings. <br> RESULTS: The final analysis included 156 respondents (RN: 54; BR: 49; RB: 53). No differences were found between the presentation orders with respect to stated choice certainty, or the proportion of respondents failing either the dominance or stability test. However, deterministic attribute grouping was associated with higher choice consistency. <br> CONCLUSION: To increase choice consistency, DCE attributes should be randomised within logical groups that may be further randomised to reduce the risk of ordering effects.

Entities:  

Year:  2020        PMID: 33174080     DOI: 10.1007/s40271-020-00475-y

Source DB:  PubMed          Journal:  Patient        ISSN: 1178-1653            Impact factor:   3.883


  21 in total

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Authors:  G Salkeld; M Ryan; L Short
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2.  Using conjoint analysis to take account of patient preferences and go beyond health outcomes: an application to in vitro fertilisation.

Authors:  M Ryan
Journal:  Soc Sci Med       Date:  1999-02       Impact factor: 4.634

3.  Response-ordering effects: a methodological issue in conjoint analysis.

Authors:  S Farrar; M Ryan
Journal:  Health Econ       Date:  1999-02       Impact factor: 3.046

4.  Conjoint analysis applications in health--a checklist: a report of the ISPOR Good Research Practices for Conjoint Analysis Task Force.

Authors:  John F P Bridges; A Brett Hauber; Deborah Marshall; Andrew Lloyd; Lisa A Prosser; Dean A Regier; F Reed Johnson; Josephine Mauskopf
Journal:  Value Health       Date:  2011-04-22       Impact factor: 5.725

5.  Use of discrete choice experiments to elicit preferences.

Authors:  M Ryan; A Bate; C J Eastmond; A Ludbrook
Journal:  Qual Health Care       Date:  2001-09

Review 6.  Discrete choice experiments in health economics: a review of the literature.

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Journal:  Pharmacoeconomics       Date:  2014-09       Impact factor: 4.981

Review 7.  Discrete choice experiments in health economics: a review of the literature.

Authors:  Esther W de Bekker-Grob; Mandy Ryan; Karen Gerard
Journal:  Health Econ       Date:  2010-12-19       Impact factor: 3.046

8.  The effect of including an opt-out option in discrete choice experiments.

Authors:  Jorien Veldwijk; Mattijs S Lambooij; Esther W de Bekker-Grob; Henriëtte A Smit; G Ardine de Wit
Journal:  PLoS One       Date:  2014-11-03       Impact factor: 3.240

9.  Using Discrete Choice Experiments to Inform the Benefit-Risk Assessment of Medicines: Are We Ready Yet?

Authors:  Caroline M Vass; Katherine Payne
Journal:  Pharmacoeconomics       Date:  2017-09       Impact factor: 4.981

10.  Discrete Choice Experiments in Health Economics: Past, Present and Future.

Authors:  Vikas Soekhai; Esther W de Bekker-Grob; Alan R Ellis; Caroline M Vass
Journal:  Pharmacoeconomics       Date:  2019-02       Impact factor: 4.981

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  3 in total

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Journal:  Patient       Date:  2021-05-05       Impact factor: 3.883

2.  Patient preferences for atopic dermatitis medications in the UK, France and Spain: a discrete choice experiment.

Authors:  Caitlin Thomas; Afaf Raibouaa; Andreas Wollenberg; Jean-Philippe Capron; Nicolas Krucien; Hayley Karn; Tommi Tervonen
Journal:  BMJ Open       Date:  2022-08-02       Impact factor: 3.006

3.  Comparing Patient Preferences for Antithrombotic Treatment During the Acute and Chronic Phases of Myocardial Infarction: A Discrete-Choice Experiment.

Authors:  Cathy Anne Pinto; Gin Nie Chua; John F P Bridges; Ella Brookes; Johanna Hyacinthe; Tommi Tervonen
Journal:  Patient       Date:  2021-09-27       Impact factor: 3.883

  3 in total

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