| Literature DB >> 3317060 |
Abstract
Chlorhexidine is widely used as a bacterial drug whose method of action has been well described in bacteria. Its fungicidal properties have been proved. We show here the effects of a sublethal dose of a preparation of digluconate of chlorhexidine on budding Candida albicans. A fungistatic action is revealed by a decrease in the percentage of budding cells, and two main types of alterations can be observed with transmission electron microscopy (T.E.M.): a loss of cytoplasmic components and a coagulation of nucleoproteins. With scanning electron microscopy (S.E.M.), the cell walls show morphological modifications.Entities:
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Year: 1987 PMID: 3317060 DOI: 10.1007/BF00769565
Source DB: PubMed Journal: Mycopathologia ISSN: 0301-486X Impact factor: 2.574