Daniel Cisternas1, Tiffany Taft2, Dustin A Carlson2, Esteban Glasinovic1, Hugo Monrroy3, Paula Rey3, Albis Hani4, Andres Ardila-Hani4, Ana Maria Leguizamo4, Claudio Bilder5, Andres Ditaranto5, Amanda Varela5, Joaquin Agotegaray5, Jose Maria Remes-Troche6, Antonio Ruiz de León7, Julio Pérez de la Serna7, Ingrid Marin8,9, Jordi Serra8,9. 1. Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Clínica Alemana de Santiago, Santiago, Chile. 2. Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. 3. Pontificia Universidad Católica de Chile, Santiago, Chile. 4. San Ignacio Hospital, Pontificia Universidad Javeriana, Bogota, Colombia. 5. Escuela de Medicina, Fundación Favaloro, Hospital Universitario, Buenos Aires, Argentina. 6. Universidad Veracruzana, Veracruz, México. 7. Hospital Clínico San Carlos, Universidad Complutense, Madrid, Spain. 8. Motility and Functional Gut Disorders Unit, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University Hospital Germans Trias i Pujol, Badalona, Spain. 9. Universitat Autonoma de Barcelona, Badalona, Spain.
Abstract
BACKGROUND: The recently developed Brief Esophageal Dysphagia Questionnaire (BEDQ) evaluates esophageal obstructive symptoms. Its initial evaluation showed strong psychometric properties. The aims of this study were to (a) translate and validate an international Spanish version of BEDQ and (b) evaluate its psychometric properties in a large Hispano-American sample of symptomatic individuals. METHODS: A Spanish BEDQ version was performed by Hispano-American experts using a Delphi process and reverse translation. Patients were prospectively recruited from seven centers in Spain and Latin America among individuals referred for high-resolution manometry (HRM). Patients completed several scores: Hospital Anxiety & Depression Scale (HADS), Eckardt score (ES), Gastroesophageal Reflux Questionnaire (GERDQ), and the BEDQ. Standardized psychometric analyses were performed. KEY RESULTS: A total of 426 patients were recruited. Spanish BEDQ showed excellent reliability (Cronbach's alpha = 0.91). Factor analysis confirmed its unidimensional character. Moderate significant correlations between BEDQ and other symptomatic scores were found, suggesting sufficient convergent validity. Patients with abnormal or obstructive HRM findings scored significantly higher when compared to normal or non-obstructive findings, respectively. Using a cutoff of 10, BEDQ showed a sensitivity of 65.38% and a specificity of 66.21% and an area under the curve of 0.71 for obstructive or major manometric diagnosis. CONCLUSIONS AND INFERENCES: A widely usable Spanish BEDQ version has been validated. We confirm its excellent psychometric properties in our patients, confirming the appropriateness of its use in different populations.
BACKGROUND: The recently developed Brief Esophageal Dysphagia Questionnaire (BEDQ) evaluates esophageal obstructive symptoms. Its initial evaluation showed strong psychometric properties. The aims of this study were to (a) translate and validate an international Spanish version of BEDQ and (b) evaluate its psychometric properties in a large Hispano-American sample of symptomatic individuals. METHODS: A Spanish BEDQ version was performed by Hispano-American experts using a Delphi process and reverse translation. Patients were prospectively recruited from seven centers in Spain and Latin America among individuals referred for high-resolution manometry (HRM). Patients completed several scores: Hospital Anxiety & Depression Scale (HADS), Eckardt score (ES), Gastroesophageal Reflux Questionnaire (GERDQ), and the BEDQ. Standardized psychometric analyses were performed. KEY RESULTS: A total of 426 patients were recruited. Spanish BEDQ showed excellent reliability (Cronbach's alpha = 0.91). Factor analysis confirmed its unidimensional character. Moderate significant correlations between BEDQ and other symptomatic scores were found, suggesting sufficient convergent validity. Patients with abnormal or obstructive HRM findings scored significantly higher when compared to normal or non-obstructive findings, respectively. Using a cutoff of 10, BEDQ showed a sensitivity of 65.38% and a specificity of 66.21% and an area under the curve of 0.71 for obstructive or major manometric diagnosis. CONCLUSIONS AND INFERENCES: A widely usable Spanish BEDQ version has been validated. We confirm its excellent psychometric properties in our patients, confirming the appropriateness of its use in different populations.
Authors: Tiffany H Taft; Dustin A Carlson; Madison Simons; Sonia Zavala; Ikuo Hirano; Nirmala Gonsalves; John E Pandolfino Journal: Gastroenterology Date: 2021-06-19 Impact factor: 33.883