Literature DB >> 33165864

Modeling Leukemia Stem Cells with Patient-Derived Induced Pluripotent Stem Cells.

André G Deslauriers1,2,3,4,5,6, Andriana G Kotini1,2,3,4, Eirini P Papapetrou7,8,9,10.   

Abstract

Patient-derived induced pluripotent stem cells (iPSCs) have recently provided a new way to model acute myeloid leukemia (AML) and other myeloid malignancies. Here, we describe methods for the generation of patient-derived iPSCs from leukemia cells and for their subsequent directed in vitro differentiation into hematopoietic cells that recapitulate features of leukemia stem cells (LSCs) and leukemic blasts.

Entities:  

Keywords:  AML; Human induced pluripotent stem cells; Reprogramming; hPSC-hematopoiesis; iPSC disease modeling

Mesh：

Year:  2021        PMID： 33165864      PMCID： PMC7821974          DOI： 10.1007/978-1-0716-0810-4_26

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  15 in total

1.  Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples.

Authors:  Keiki Kumano; Shunya Arai; Masataka Hosoi; Kazuki Taoka; Naoya Takayama; Makoto Otsu; Genta Nagae; Koki Ueda; Kumi Nakazaki; Yasuhiko Kamikubo; Koji Eto; Hiroyuki Aburatani; Hiromitsu Nakauchi; Mineo Kurokawa
Journal:  Blood       Date:  2012-05-16       Impact factor: 22.113

2.  Generation of transgene-free human induced pluripotent stem cells with an excisable single polycistronic vector.

Authors:  Eirini P Papapetrou; Michel Sadelain
Journal:  Nat Protoc       Date:  2011-08-04       Impact factor: 13.491

3.  Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.

Authors:  Andriana G Kotini; Chan-Jung Chang; Arthur Chow; Han Yuan; Tzu-Chieh Ho; Tiansu Wang; Shailee Vora; Alexander Solovyov; Chrystel Husser; Malgorzata Olszewska; Julie Teruya-Feldstein; Deepak Perumal; Virginia M Klimek; Alexandros Spyridonidis; Raajit K Rampal; Lewis Silverman; E Premkumar Reddy; Elli Papaemmanuil; Samir Parekh; Benjamin D Greenbaum; Christina S Leslie; Michael G Kharas; Eirini P Papapetrou
Journal:  Cell Stem Cell       Date:  2017-02-16       Impact factor: 24.633

4.  In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.

Authors:  Giovanni Amabile; Robert S Welner; Cesar Nombela-Arrieta; Anna Morena D'Alise; Annalisa Di Ruscio; Alexander K Ebralidze; Yevgenya Kraytsberg; Min Ye; Olivier Kocher; Donna S Neuberg; Konstantin Khrapko; Leslie E Silberstein; Daniel G Tenen
Journal:  Blood       Date:  2012-12-04       Impact factor: 22.113

5.  Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors:  Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal:  Cell       Date:  2007-11-30       Impact factor: 41.582

6.  Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

Authors:  Angel Raya; Ignasi Rodríguez-Pizà; Guillermo Guenechea; Rita Vassena; Susana Navarro; María José Barrero; Antonella Consiglio; Maria Castellà; Paula Río; Eduard Sleep; Federico González; Gustavo Tiscornia; Elena Garreta; Trond Aasen; Anna Veiga; Inder M Verma; Jordi Surrallés; Juan Bueren; Juan Carlos Izpisúa Belmonte
Journal:  Nature       Date:  2009-05-31       Impact factor: 49.962

7.  Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders.

Authors:  Zhaohui Ye; Huichun Zhan; Prashant Mali; Sarah Dowey; Donna M Williams; Yoon-Young Jang; Chi V Dang; Jerry L Spivak; Alison R Moliterno; Linzhao Cheng
Journal:  Blood       Date:  2009-10-01       Impact factor: 22.113

8.  Disease-specific induced pluripotent stem cells.

Authors:  In-Hyun Park; Natasha Arora; Hongguang Huo; Nimet Maherali; Tim Ahfeldt; Akiko Shimamura; M William Lensch; Chad Cowan; Konrad Hochedlinger; George Q Daley
Journal:  Cell       Date:  2008-08-07       Impact factor: 41.582

9.  Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.

Authors:  Luis F Z Batista; Matthew F Pech; Franklin L Zhong; Ha Nam Nguyen; Kathleen T Xie; Arthur J Zaug; Sharon M Crary; Jinkuk Choi; Vittorio Sebastiano; Athena Cherry; Neelam Giri; Marius Wernig; Blanche P Alter; Thomas R Cech; Sharon A Savage; Renee A Reijo Pera; Steven E Artandi
Journal:  Nature       Date:  2011-05-22       Impact factor: 49.962

10.  Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs.

Authors:  Chan-Jung Chang; Andriana G Kotini; Malgorzata Olszewska; Maria Georgomanoli; Julie Teruya-Feldstein; Henrik Sperber; Roberto Sanchez; Robert DeVita; Timothy J Martins; Omar Abdel-Wahab; Robert K Bradley; Eirini P Papapetrou
Journal:  Stem Cell Reports       Date:  2018-04-19       Impact factor: 7.765
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