AIMS: The aim of this study was to assess clinical and prognosis differences in patients with COVID-19 and STEMI. METHODS AND RESULTS: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19 patients) and previous coronary artery disease (more frequent in COVID-19 patients), clinical characteristics were similar between the groups, but COVID-19 patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046) and GP IIb/IIIa inhibitor administration (20.9% vs 11.2%, p=0.007) were more frequent in COVID-19 patients, who had an increased in-hospital mortality (23.1% vs 5.7%, p<0.0001), that remained consistent after adjustment for age, sex, Killip class and ischaemic time (OR 4.85, 95% CI: 2.04-11.51; p<0.001). COVID-19 patients had an increase of stent thrombosis (3.3% vs 0.8%, p=0.020) and cardiogenic shock development after PCI (9.9% vs 3.8%, p=0.007). CONCLUSIONS: Our study revealed a significant increase in in-hospital mortality, stent thrombosis and cardiogenic shock development after PCI in patients with STEMI and COVID-19 in comparison with contemporaneous non-COVID-19 STEMI patients. Visual summary. In-hospital outcomes of COVID-19 ST-elevation myocardial infarction patients.
AIMS: The aim of this study was to assess clinical and prognosis differences in patients with COVID-19 and STEMI. METHODS AND RESULTS: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19patients) and previous coronary artery disease (more frequent in COVID-19patients), clinical characteristics were similar between the groups, but COVID-19patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046) and GP IIb/IIIa inhibitor administration (20.9% vs 11.2%, p=0.007) were more frequent in COVID-19patients, who had an increased in-hospital mortality (23.1% vs 5.7%, p<0.0001), that remained consistent after adjustment for age, sex, Killip class and ischaemic time (OR 4.85, 95% CI: 2.04-11.51; p<0.001). COVID-19patients had an increase of stent thrombosis (3.3% vs 0.8%, p=0.020) and cardiogenic shock development after PCI (9.9% vs 3.8%, p=0.007). CONCLUSIONS: Our study revealed a significant increase in in-hospital mortality, stent thrombosis and cardiogenic shock development after PCI in patients with STEMI and COVID-19 in comparison with contemporaneous non-COVID-19 STEMI patients. Visual summary. In-hospital outcomes of COVID-19 ST-elevation myocardial infarctionpatients.
Authors: Marwan Saad; Kevin F Kennedy; Hafiz Imran; David W Louis; Ernie Shippey; Athena Poppas; Kenneth E Wood; J Dawn Abbott; Herbert D Aronow Journal: JAMA Date: 2021-11-16 Impact factor: 56.272
Authors: Alexander Fardman; Doron Zahger; Katia Orvin; Daniel Oren; Natalia Kofman; Jameel Mohsen; Or Tsafrir; Elad Asher; Ronen Rubinshtein; Jafari Jamal; Roi Efraim; Majdi Halabi; Yacov Shacham; Lior Henri Fortis; Tal Cohen; Robert Klempfner; Amit Segev; Roy Beigel; Shlomi Matetzky Journal: PLoS One Date: 2021-06-18 Impact factor: 3.240
Authors: Armando Del Prete; Francesca Conway; Domenico G Della Rocca; Giuseppe Biondi-Zoccai; Francesco De Felice; Carmine Musto; Marco Picichè; Eugenio Martuscelli; Andrea Natale; Francesco Versaci Journal: Card Electrophysiol Clin Date: 2021-10-30