| Literature DB >> 33164331 |
Meera Krishnamoorthy1, Evan Nadler2, Susma Vaidya3.
Abstract
Confluent and reticulated papillomatosis (CARP), a rare dermatologic disorder characterized by hyperpigmented papules that subsequently develop into plaques with reticulated margins, is frequently confused with acanthosis nigricans. The aetiology and pathogenesis of CARP is not yet fully understood, but it is often present in individuals with obesity and PCOS. This case report describes an African American adolescent female with obesity with a rash diagnosed as CARP after unsuccessful treatment with antifungals and corticosteroids. Her dermatosis proved recalcitrant to antibiotics and metformin but started to resolve immediately after bariatric surgery. This case report supports insulin resistance as a contributor to CARP's pathogenesis and as well as its association with obesity. Clinically significant weight reduction should be considered in the management of this challenging skin condition.Entities:
Keywords: confluent and reticulated papillomatosis and treatment; confluent and reticulated papillomatous and obesity; dermatosis and bariatric surgery
Year: 2020 PMID: 33164331 DOI: 10.1111/cob.12427
Source DB: PubMed Journal: Clin Obes ISSN: 1758-8103