| Literature DB >> 33163602 |
Olohirere T Ezomo1, Daniel Sun2, Christian Gronbeck3, Melvyn A Harrington2, Mohamad J Halawi2.
Abstract
BACKGROUND: Little is known about the persistence of health disparities in joint arthroplasty. The objective of this study was to update our knowledge on the state of racial and ethnic disparities in total hip arthroplasty (THA).Entities:
Keywords: 30-Day adverse events; Ethnicity; Health disparities; Race; Total hip arthroplasty
Year: 2020 PMID: 33163602 PMCID: PMC7609456 DOI: 10.1016/j.artd.2020.10.002
Source DB: PubMed Journal: Arthroplast Today ISSN: 2352-3441
Baseline and perioperative characteristics of the study cohorts.
| Variable | Non-Hispanic white | Non-Hispanic black or African American | Hispanic or Latino | Asian | American Indian or Alaska Native | Native Hawaiian or Pacific Islander | |
|---|---|---|---|---|---|---|---|
| Control group | Study groups | ||||||
| N = 155,870 | 116,129 (74.5%) | 11,574 (7.4%) | 4107 (2.6%) | 2140 (1.4%) | 594 (0.4%) | 417 (0.3%) | – |
| Demographic characteristics | |||||||
| Age (years) | 65.3 ± 11.2 | 59.9 ± 11.7∗ | 59.9 ± 13.0∗ | 64.9 ± 12.6 | 58.4 ± 12.0∗ | 61.7 ± 11.2∗ | |
| Sex | |||||||
| Female | 63,697 (54.8%) | 6113 (52.8%)∗ | 2122 (51.7%)∗ | 1423 (66.5%)∗ | 292 (49.2%)∗ | 198 (47.5%)∗ | |
| Male | 52,427 (45.2%) | 5461 (47.1%)∗ | 1985 (48.3%)∗ | 717 (33.5%)∗ | 302 (50.8%)∗ | 219 (52.5%)∗ | |
| Body mass index (kg/m2) | 30.3 ± 6.3 | 31.7 ± 6.8∗ | 30.8 ± 5.9∗ | 26.9 ± 5.4∗ | 31.2 ± 6.3∗ | 31.6 ± 6.2∗ | |
| Current smoker | 13,993 (12.1%) | 2794 (24.1%)∗ | 553 (13.5%)∗ | 162 (7.6%)∗ | 136 (22.9%)∗ | 69 (16.6%)∗ | |
| Chronic steroid use | 4038 (3.5%) | 573 (5.0%)∗ | 218 (5.3%)∗ | 92 (4.3%) | 28 (4.7%) | 13 (3.1%) | |
| ASA classification | 2.4 ± 0.6 | 2.5 ± 0.6∗ | 2.4 ± 0.6 | 2.3 ± 0.6∗ | 2.5 ± 0.6∗ | 2.4 ± 0.6 | |
| Functional status | |||||||
| Independent | 113,818 (98.4%) | 11,237 (97.5%)∗ | 3959 (97.0%)∗ | 2064 (97.9%) | 582 (98.0%) | 399 (97.1%) | |
| Partially or completely dependent | 1903 (1.6%) | 293 (2.5%)∗ | 121 (3.0%)∗ | 44 (2.1%) | 12 (2.0%) | 12 (3.0%) | |
| Preoperative living environment | .298 | ||||||
| Admitted directly from the home | 115, 686 (99.7%) | 11,510 (99.6%) | 4095 (99.7%) | 2133 (99.7%) | 592 (99.7%) | 415 (99.5%) | |
| Admitted from a facility | 363 (0.3%) | 51 (0.4%) | 11 (0.3%) | 7 (0.3%) | 2 (0.3%) | 2 (0.5%) | |
| Comorbidities | |||||||
| Diabetes | 12,966 (11.2%) | 2123 (18.3%)∗ | 696 (17.0%)∗ | 306 (14.3%)∗ | 79 (13.3%) | 70 (16.8%)∗ | |
| Hypertension | 65,071 (56.0%) | 8040 (69.5%)∗ | 2162 (52.6%)∗ | 1225 (57.2%) | 284 (47.8%)∗ | 246 (58.9%) | |
| Chronic obstructive pulmonary disease | 4692 (4.0%) | 480 (4.2%) | 111 (2.7%)∗ | 33 (1.5%)∗ | 17 (2.9%) | 11 (2.6%) | |
| Chronic heart failure | 311 (0.3%) | 50 (0.4%)∗ | 8 (0.2%) | 3 (0.1%) | 4 (0.7%) | 3 (0.7%) | |
| Anemia | 20,518 (18.5%) | 3843 (34.4%)∗ | 866 (22.1%)∗ | 392 (19.1%) | 143 (25.4%)∗ | 79 (20.3%) | |
| Metastatic cancer | 209 (0.2%) | 23 (0.2%) | 6 (0.2%) | 4 (0.2%) | 2 (0.3%) | 1 (0.2%) | .929 |
| Bleeding disorder | 2549 (2.2%) | 230 (2.0%) | 74 (1.8%) | 36 (1.7%) | 5 (0.8%) | 1 (0.2%)∗ | |
| Dyspnea | 5280 (4.6%) | 627 (5.4%)∗ | 115 (2.8%)∗ | 27 (1.3%)∗ | 15 (2.5%) | 4 (1.0%)∗ | |
| Ascites | 23 (0.02%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | .589 |
| Chronic kidney disease | 2640 (2.4%) | 577 (5.3%)∗ | 100 (2.6%) | 50 (2.5%) | 5 (0.9%) | 16 (4.4%) | |
| Perioperative characteristics | |||||||
| Diagnosis | |||||||
| Primary osteoarthritis | 110,062 (94.5%) | 10,168 (87.9%)∗ | 3576 (87.1%)∗ | 1894 (88.0%)∗ | 510 (85.9%)∗ | 381 (91.4%) | |
| Inflammatory arthritis | 287 (0.3%) | 48 (0.4%)∗ | 54 (1.3%)∗ | 12 (0.6%)∗ | 8 (1.4%)∗ | 1 (0.2%) | |
| Posttraumatic arthritis | 665 (0.6%) | 82 (0.7%)∗ | 42 (1.0%)∗ | 10 (0.5%)∗ | 16 (2.7%)∗ | 2 (0.5%) | |
| Childhood dysplasia | 598 (0.5%) | 50 (0.4%)∗ | 70 (1.7%)∗ | 37 (1.7%)∗ | 8 (1.4%)∗ | 4 (1.0%) | |
| Osteonecrosis | 4517 (3.9%) | 1226 (10.6%)∗ | 365 (8.9%)∗ | 187 (8.7%)∗ | 52 (8.8%)∗ | 29 (7.0%) | |
| Bilateral procedure | 667 (0.6%) | 87 (0.8%) | 28 (0.7%) | 66 (3.1%)∗ | 2 (0.3%) | 9 (2.2%)∗ | |
| Procedure length >100 minutes | 37,798 (32.6%) | 5146 (44.5%)∗ | 1718 (41.8%)∗ | 763 (35.7%)∗ | 230 (38.7%)∗ | 240 (57.8%)∗ | |
ASA, American Society of Anesthesiologists physical classification system.
Values are presented as the mean and standard deviation for continuous variables or the frequency and percentage for binary variables. P values indicate significant overall differences among all racial groups for a particular patient factor, and an asterisk (∗) denotes attribution of that significance to a particular study group as compared with the white race (control group). For nominal variables, overall P values and direct group comparisons were obtained using the chi-square tests. For continuous variables, overall P values were obtained from one-way analysis of variance (ANOVA) and direct group comparisons through a post hoc Dunnett test.
Significant P-values (P < .05) are bolded.
Includes 20,909 (13.4%) patients undergoing elective THA with an unreported race or ethnicity.
Multivariate regression analysis of 30-day outcome measures relative to the white race.
| Outcome | Non-Hispanic black or African American | Hispanic or Latino | Asian | American Indian or Alaska Native | Native Hawaiian or Pacific Islander | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study groups | |||||||||||||||
| OR | CI | OR | CI | OR | CI | OR | CI | OR | CI | ||||||
| Mortality | 1.54 | 0.95 to 2.48 | .073 | 1.20 | 0.49 to 2.96 | .690 | 0.87 | 0.21 to 3.54 | .845 | 1.78 | 0.24 to 12.9 | .570 | No observations | ||
| Readmission | 0.98 | 0.88 to 1.10 | .856 | 1.06 | 0.88 to 1.27 | .556 | 0.81 | 0.61 to 1.07 | .146 | 1.18 | 0.76 to 1.84 | .460 | 0.66 | 0.34 to 1.28 | .221 |
| Reoperation | 0.90 | 0.78 to 1.04 | .148 | 0.87 | 0.68 to 1.12 | .286 | 0.82 | 0.57 to 1.19 | .308 | 1.91 | 1.23 to 2.97 | 0.96 | 0.47 to 1.94 | .907 | |
| Length of stay (days) | 0.18 | 0.14 to 0.23 | 0.23 | 0.16 to 0.32 | −0.08 | −1.18 to 0.14 | .091 | 0.54 | 0.35 to 0.73 | −0.10 | −0.31 to 0.12 | .390 | |||
| Inpatient stay (>2 days) | 1.27 | 1.21 to 1.32 | 1.25 | 1.17 to 1.34 | 0.84 | 0.77 to 0.92 | 2.06 | 1.72 to 2.46 | 0.82 | 0.67 to 1.01 | .062 | ||||
| Any complication | 1.15 | 1.01 to 1.30 | 1.21 | 0.98 to 1.50 | .070 | 1.07 | 0.78 to 1.47 | .674 | 0.76 | 0.39 to 1.48 | .425 | 0.78 | 0.37 to 1.66 | .527 | |
| Any surgical complication | 1.21 | 1.04 to 1.40 | 1.28 | 1.00 to 1.64 | 1.19 | 0.81 to 1.73 | .377 | 0.73 | 0.32 to 1.64 | .443 | 0.98 | 0.44 to 2.20 | .959 | ||
| Any medical complication | 1.20 | 1.00 to 1.45 | 1.01 | 0.71 to 1.44 | .968 | 0.81 | 0.47 to 1.40 | .436 | 0.66 | 0.21 to 2.05 | .468 | 0.58 | 0.14 to 2.34 | .446 | |
Regression output for all case groups was defined relative to the white race (control group). Patient factors previously demonstrating significant differences between the specific racial or ethnic group and white race (Table 1) were controlled for in the regression analyses.
Significant P-values (P < .05) are bolded.
Values represent correlation coefficients from a multivariate linear regression.