Appeal and Use of Customizable E-cigarette Product Features in Adolescents.

OBJECTIVES: We evaluated the appeal and use of e-cigarette product features in a sample of high school students in Connecticut.
METHODS: In 2015, we conducted school-wide surveys in 8 high schools and analyzed data from 1765 students (877 susceptible tobacco-naïve never-e-cigarette users, 315 susceptible tobacco-exposed never-e-cigarette users, and 656 current e-cigarette users). Students were asked: "What is cool about e-cigarettes?" Response options included e-liquid ingredients (eg, flavors, nicotine content, propylene glycol/vegetable glycerin ratio [ie, PG/VG), the heating source (eg, battery), and physical design (eg, color, shape, appearance). Students were asked: "How do you customize your e-cigarette?" (Change flavors, voltage, PG/VG levels, temperature, skin/tank color, other) and use of nicotine in the e-liquid (yes/no). Multivariable regression assessed associations between current e-cigarette users' customization and e-cigarette use frequency (#days/month).
RESULTS: Flavors were the most appealing product feature among all groups. Among current users, using nicotine e-liquid was more prevalent than changing flavors (44.2% vs 29.6%). Using nicotine e-liquids and changing PG/vG ratios were associated with more frequent e-cigarette use among current users.
CONCLUSIONS: These findings can inform tobacco regulatory actions that put forth evidence-based recommendations to manufacture e-liquid flavors, nicotine concentrations and PG/VG ratios that prevent e-cigarette initiation and escalation of use.