Literature DB >> 3316256

A repetitive sequence element 3' of the human c-Ha-ras1 gene has enhancer activity.

J B Cohen1, M V Walter, A D Levinson.   

Abstract

Efficient expression of the human c-Ha-ras1 gene requires sequences 3' of those specifying the polyadenylation of its transcripts. These sequences can stimulate the expression of heterologous genes in a manner largely independent of position and orientation, arguing that they possess a transcriptional enhancing activity that regulates the c-Ha-ras1 promoter. As this element is associated with a repetitive domain that is highly polymorphic, it is possible that the activity of this enhancer is variable within the human population.

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Year:  1987        PMID： 3316256     DOI： 10.1002/jcp.1041330415

Source DB:  PubMed          Journal:  J Cell Physiol Suppl        ISSN： 0737-1462


  9 in total

1.  Minisatellite alterations in ZRT1 mutants occur via RAD52-dependent and RAD52-independent mechanisms in quiescent stationary phase yeast cells.

Authors:  Maire K Kelly; Bonnie Alver; David T Kirkpatrick
Journal:  DNA Repair (Amst)       Date:  2011-04-22

2.  Length and sequence heterozygosity differentially affect HRAS1 minisatellite stability during meiosis in yeast.

Authors:  Peter A Jauert; David T Kirkpatrick
Journal:  Genetics       Date:  2005-04-16       Impact factor: 4.562

3.  Members of the rel/NF-kappa B family of transcriptional regulatory proteins bind the HRAS1 minisatellite DNA sequence.

Authors:  W L Trepicchio; T G Krontiris
Journal:  Nucleic Acids Res       Date:  1992-05-25       Impact factor: 16.971

4.  Distribution of Ha-ras alleles in patients with colorectal cancer and Crohn's disease.

Authors:  R Klingel; P Mittelstaedt; W G Dippold; K H Meyer zum Büschenfelde
Journal:  Gut       Date:  1991-12       Impact factor: 23.059

5.  The role of CSM3, MRC1, and TOF1 in minisatellite stability and large loop DNA repair during meiosis in yeast.

Authors:  Andrea R LeClere; John K Yang; David T Kirkpatrick
Journal:  Fungal Genet Biol       Date:  2012-11-17       Impact factor: 3.495

6.  RAD1 controls the meiotic expansion of the human HRAS1 minisatellite in Saccharomyces cerevisiae.

Authors:  Peter A Jauert; Sharon N Edmiston; Kathleen Conway; David T Kirkpatrick
Journal:  Mol Cell Biol       Date:  2002-02       Impact factor: 4.272

7.  Ha-ras rare alleles in breast cancer susceptibility.

Authors:  K Conway; S Edmiston; D B Fried; B S Hulka; P A Garrett; E T Liu
Journal:  Breast Cancer Res Treat       Date:  1995-07       Impact factor: 4.872

8.  Adenovirus VAI-RNA regulates gene expression by controlling stability of ribosome-bound RNAs.

Authors:  R Strijker; D T Fritz; A D Levinson
Journal:  EMBO J       Date:  1989-09       Impact factor: 11.598

9.  Relationship of H-ras-1, L-myc, and p53 polymorphisms with lung cancer risk and prognosis.

Authors:  A Weston; N E Caporaso; L S Perrin; H Sugimura; S Tamai; T G Krontiris; B F Trump; R N Hoover; C C Harris
Journal:  Environ Health Perspect       Date:  1992-11       Impact factor: 9.031
  9 in total

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