Literature DB >> 3316240

Antibiotic prophylaxis with cefuroxime in arthroplasty of the knee.

D P Johnson1.   

Abstract

A randomised prospective trial was undertaken of antibiotic prophylaxis given at various intervals before inflation of the tourniquet for arthroplasty of the knee. Cefuroxime assays of bone and subcutaneous fat from samples collected throughout the operation demonstrated that an interval of 10 minutes was necessary to obtain adequate prophylaxis. Improvement in the timing of antibiotic prophylaxis may result in a reduction in the incidence of infection.

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Year:  1987        PMID： 3316240     DOI： 10.1302/0301-620X.69B5.3316240

Source DB:  PubMed          Journal:  J Bone Joint Surg Br        ISSN： 0301-620X


  10 in total

1.  Pharmacodynamic model for β-lactam regimens used in surgical prophylaxis: model-based evaluation of standard dosing regimens.

Authors:  XiangQing Song; MingHui Long
Journal:  Int J Clin Pharm       Date:  2018-08-16

2.  Skeletal muscle and plasma concentrations of cefazolin.

Authors:  P C Jutte; J J W Ploegmakers; S K Bulstra
Journal:  Br J Anaesth       Date:  2016-07       Impact factor: 9.166

3.  Tissue concentrations of third-generation cephalosporins (ceftazidime and ceftriaxone) in lower extremity tissues using a tourniquet.

Authors:  N Papaioannou; L Kalivas; J Kalavritinos; S Tsourvakas
Journal:  Arch Orthop Trauma Surg       Date:  1994       Impact factor: 3.067

Review 4.  [Antibiotic prophylaxis in primary and revision hip arthroplasty: what is the evidence?].

Authors:  G Gradl; C Horn; L K L Postl; T Miethke; H Gollwitzer
Journal:  Orthopade       Date:  2011-06       Impact factor: 1.087

5.  Are bone and serum cefazolin concentrations adequate for antimicrobial prophylaxis?

Authors:  Koji Yamada; Kunihiro Matsumoto; Fumiaki Tokimura; Hiroshi Okazaki; Sakae Tanaka
Journal:  Clin Orthop Relat Res       Date:  2011-10-04       Impact factor: 4.176

6.  Compliance with national guidelines for antibiotic prophylaxis in hip fracture patients: a quality assessment study of 13 329 patients in the Norwegian Hip Fracture Register.

Authors:  Tom Lian; Eva Dybvik; Jan-Erik Gjertsen; Håvard Dale; Marianne Westberg; Lars Nordsletten; Wender Figved
Journal:  BMJ Open       Date:  2020-05-20       Impact factor: 2.692

7.  Regional Intraosseous Administration of Prophylactic Antibiotics is More Effective Than Systemic Administration in a Mouse Model of TKA.

Authors:  Simon W Young; Tim Roberts; Sarah Johnson; James P Dalton; Brendan Coleman; Siouxsie Wiles
Journal:  Clin Orthop Relat Res       Date:  2015-07-30       Impact factor: 4.176

Review 8.  Systematic review and meta-analysis of randomized controlled trials of antibiotics and antiseptics for preventing infection in people receiving primary total hip and knee prostheses.

Authors:  Jeffrey Voigt; Michael Mosier; Rabih Darouiche
Journal:  Antimicrob Agents Chemother       Date:  2015-08-10       Impact factor: 5.191

Review 9.  Antibiotics and antiseptics for preventing infection in people receiving revision total hip and knee prostheses: a systematic review of randomized controlled trials.

Authors:  Jeffrey Voigt; Michael Mosier; Rabih Darouiche
Journal:  BMC Infect Dis       Date:  2016-12-12       Impact factor: 3.090

10.  Effects of tourniquet inflation on peri- and postoperative cefuroxime concentrations in bone and tissue.

Authors:  Pelle Hanberg; Mats Bue; Jesper Kabel; Andrea René Jørgensen; Christian Jessen; Kjeld Søballe; Maiken Stilling
Journal:  Acta Orthop       Date:  2021-08-02       Impact factor: 3.717
  10 in total

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