Literature DB >> 3316038

Extensive homology between the leukotoxin of Pasteurella haemolytica A1 and the alpha-hemolysin of Escherichia coli.

C A Strathdee1, R Y Lo.   

Abstract

The 19.8- and 101.9-kilodalton leukotoxin proteins of Pasteurella haemolytica (LKTC and LKTA, respectively) share extensive homology with the HLYC and HLYA alpha-hemolysin proteins of Escherichia coli. The leukotoxin LKTA protein cross-reacts with hemolysin-specific antisera in Western blot (immunoblot) analysis, indicating that it shares epitopes with the alpha-hemolysin HLYA protein. Both LKTA and HLYA contain a conserved hydrophobic region, as well as a set of tandemly repeated domains. These features have been implicated in the lytic function of the alpha-hemolysin.

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Year:  1987        PMID： 3316038      PMCID： PMC260059          DOI： 10.1128/iai.55.12.3233-3236.1987

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  22 in total

Review 1.  Empirical predictions of protein conformation.

Authors:  P Y Chou; G D Fasman
Journal:  Annu Rev Biochem       Date:  1978       Impact factor: 23.643

2.  Cytotoxin of Pasteurella haemolytica acting on bovine leukocytes.

Authors:  P E Shewen; B N Wilkie
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441

3.  A simple method for displaying the hydropathic character of a protein.

Authors:  J Kyte; R F Doolittle
Journal:  J Mol Biol       Date:  1982-05-05       Impact factor: 5.469

4.  Evidence of species specificity in the cytocidal effects of Pasteurella haemolytica.

Authors:  K L Kaehler; R J Markham; C C Muscoplat; D W Johnson
Journal:  Infect Immun       Date:  1980-11       Impact factor: 3.441

Review 5.  A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle.

Authors:  W D Yates
Journal:  Can J Comp Med       Date:  1982-07

6.  Identification of two different hemolysin determinants in uropathogenic Proteus isolates.

Authors:  R A Welch
Journal:  Infect Immun       Date:  1987-09       Impact factor: 3.441

7.  Spontaneous deletions and flanking regions of the chromosomally inherited hemolysin determinant of an Escherichia coli O6 strain.

Authors:  J Hacker; S Knapp; W Goebel
Journal:  J Bacteriol       Date:  1983-06       Impact factor: 3.490

8.  Characterization of Escherichia coli hemolysins conferring quantitative differences in virulence.

Authors:  R A Welch; S Falkow
Journal:  Infect Immun       Date:  1984-01       Impact factor: 3.441

9.  Purification and partial characterization of a macrophage cytotoxin from Pasteurella haemolytica.

Authors:  M E Himmel; M D Yates; L H Lauerman; P G Squire
Journal:  Am J Vet Res       Date:  1982-05       Impact factor: 1.156

10.  Interaction of Pasteurella haemolytica with bovine neutrophils: identification and partial characterization of a cytotoxin.

Authors:  C S Baluyut; R R Simonson; W J Bemrick; S K Maheswaran
Journal:  Am J Vet Res       Date:  1981-11       Impact factor: 1.156
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  58 in total

1.  Regulation of leukotoxin in leukotoxic and nonleukotoxic strains of Actinobacillus actinomycetemcomitans.

Authors:  J Spitznagel; E Kraig; D Kolodrubetz
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

2.  Mutations affecting pore formation by haemolysin from Escherichia coli.

Authors:  A Ludwig; A Schmid; R Benz; W Goebel
Journal:  Mol Gen Genet       Date:  1991-04

Review 3.  The different hemolysins of Escherichia coli.

Authors:  L Beutin
Journal:  Med Microbiol Immunol       Date:  1991       Impact factor: 3.402

4.  Sequence of the lktB gene from Actinobacillus actinomycetemcomitans.

Authors:  J M Guthmiller; D Kolodrubetz; M P Cagle; E Kraig
Journal:  Nucleic Acids Res       Date:  1990-09-11       Impact factor: 16.971

5.  Cloning and expression of the leukotoxin gene from Actinobacillus actinomycetemcomitans.

Authors:  D Kolodrubetz; T Dailey; J Ebersole; E Kraig
Journal:  Infect Immun       Date:  1989-05       Impact factor: 3.441

6.  In vivo effects of intravascularly applied Escherichia coli hemolysin: dissociation between induction of granulocytopenia and lethality in monkeys.

Authors:  D Vagts; H P Dienes; P J Barth; H Ronneberger; K D Hungerer; S Bhakdi
Journal:  Med Microbiol Immunol       Date:  1993-03       Impact factor: 3.402

Review 7.  The RTX pore-forming toxin α-hemolysin of uropathogenic Escherichia coli: progress and perspectives.

Authors:  Travis J Wiles; Matthew A Mulvey
Journal:  Future Microbiol       Date:  2013-01       Impact factor: 3.165

8.  Effects of Pasteurella haemolytica A1 culture supernatant on mechanisms controlling bovine alveolar macrophage oxygen radical production.

Authors:  P D Conlon; P E Shewen; S F Donnelly; J P Burger
Journal:  Can J Vet Res       Date:  1990-04       Impact factor: 1.310

9.  Functional replacement of the hemolysin A transport signal by a different primary sequence.

Authors:  F Zhang; D I Greig; V Ling
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-01       Impact factor: 11.205

10.  The HpmA hemolysin is more common than HlyA among Proteus isolates.

Authors:  K G Swihart; R A Welch
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441
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