Literature DB >> 33159158

Neutrophils in liver diseases: pathogenesis and therapeutic targets.

Kai Liu1,2, Fu-Sheng Wang3,4, Ruonan Xu5.   

Abstract

Previously, it was assumed that peripheral neutrophils are a homogeneous population that displays antimicrobial functions. However, recent data have revealed that neutrophils are heterogeneous and are additionally involved in tissue damage and immune regulation. The phenotypic and functional plasticity of neutrophils has been identified in patients with cancer, inflammatory disorders, infections, and other diseases. Currently, neutrophils, with their autocrine, paracrine, and immune modulation functions, have been shown to be involved in liver diseases, including viral hepatitis, nonalcoholic steatohepatitis, alcoholic liver disease, liver fibrosis, cirrhosis, liver failure, and liver cancer. Accordingly, this review summarizes the role of neutrophils in liver diseases.

Entities:  

Keywords:  Immunotherapy; Innate immunity; Liver disease; Liver injury; Neutrophil

Mesh：

Year:  2020        PMID： 33159158      PMCID： PMC7852892          DOI： 10.1038/s41423-020-00560-0

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  82 in total

Review 1.  Neutrophil-macrophage cooperation and its impact on tissue repair.

Authors:  Tiffany Bouchery; Nicola Harris
Journal:  Immunol Cell Biol       Date:  2019-03       Impact factor: 5.126

Review 2.  Neutrophils as protagonists and targets in chronic inflammation.

Authors:  Oliver Soehnlein; Sabine Steffens; Andrés Hidalgo; Christian Weber
Journal:  Nat Rev Immunol       Date:  2017-03-13       Impact factor: 53.106

Review 3.  Immunology in the liver--from homeostasis to disease.

Authors:  Felix Heymann; Frank Tacke
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2016-01-13       Impact factor: 46.802

Review 4.  The role of neutrophils in the development of liver diseases.

Authors:  Ruonan Xu; Huihuang Huang; Zheng Zhang; Fu-Sheng Wang
Journal:  Cell Mol Immunol       Date:  2014-03-17       Impact factor: 11.530

5.  Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.

Authors:  Saurav Roy Choudhury; Liane Babes; Jennifer J Rahn; Bo-Young Ahn; Kimberly-Ann R Goring; Jennifer C King; Arthur Lau; Björn Petri; Xiaoguang Hao; Andrew K Chojnacki; Ajitha Thanabalasuriar; Erin F McAvoy; Sébastien Tabariès; Christoph Schraeder; Kamala D Patel; Peter M Siegel; Karen A Kopciuk; David C Schriemer; Daniel A Muruve; Margaret M Kelly; Bryan G Yipp; Paul Kubes; Stephen M Robbins; Donna L Senger
Journal:  Cell       Date:  2019-08-22       Impact factor: 41.582

Review 6.  How Neutrophils Meet Their End.

Authors:  Shelley M Lawrence; Ross Corriden; Victor Nizet
Journal:  Trends Immunol       Date:  2020-04-14       Impact factor: 16.687

7.  Granulocyte colony-stimulating factor inhibits the mitochondria-dependent activation of caspase-3 in neutrophils.

Authors:  Nikolai A Maianski; Frederik P J Mul; Jaap D van Buul; Dirk Roos; Taco W Kuijpers
Journal:  Blood       Date:  2002-01-15       Impact factor: 22.113

8.  In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.

Authors:  Janesh Pillay; Ineke den Braber; Nienke Vrisekoop; Lydia M Kwast; Rob J de Boer; José A M Borghans; Kiki Tesselaar; Leo Koenderman
Journal:  Blood       Date:  2010-04-21       Impact factor: 22.113

Review 9.  Innate immune cells in cirrhosis.

Authors:  Christine Bernsmeier; Schalk van der Merwe; Axel Périanin
Journal:  J Hepatol       Date:  2020-03-30       Impact factor: 25.083

10.  Phosphatidylserine externalization, "necroptotic bodies" release, and phagocytosis during necroptosis.

Authors:  Sefi Zargarian; Inbar Shlomovitz; Ziv Erlich; Aria Hourizadeh; Yifat Ofir-Birin; Ben A Croker; Neta Regev-Rudzki; Liat Edry-Botzer; Motti Gerlic
Journal:  PLoS Biol       Date:  2017-06-26       Impact factor: 8.029
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  14 in total

Review 1.  Neutrophils as potential therapeutic targets in hepatocellular carcinoma.

Authors:  Daniel Geh; Jack Leslie; Rob Rumney; Helen L Reeves; Thomas G Bird; Derek A Mann
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2022-01-12       Impact factor: 46.802

Review 2.  Immune-related pathogenesis and therapeutic strategies of nonalcoholic steatohepatitis.

Authors:  Ki Wung Chung; Ye Eun Cho; Seung-Jin Kim; Seonghwan Hwang
Journal:  Arch Pharm Res       Date:  2022-04-07       Impact factor: 4.946

3.  Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure.

Authors:  Jing Ma; Adrien Guillot; Zhihong Yang; Bryan Mackowiak; Seonghwan Hwang; Ogyi Park; Brandon J Peiffer; Ali Reza Ahmadi; Luma Melo; Praveen Kusumanchi; Nazmul Huda; Romil Saxena; Yong He; Yukun Guan; Dechun Feng; Pau Sancho-Bru; Mengwei Zang; Andrew MacGregor Cameron; Ramon Bataller; Frank Tacke; Zhaoli Sun; Suthat Liangpunsakul; Bin Gao
Journal:  J Clin Invest       Date:  2022-07-15       Impact factor: 19.456

4.  Anti-CD47 antibody treatment attenuates liver inflammation and fibrosis in experimental non-alcoholic steatohepatitis models.

Authors:  Taesik Gwag; Eric Ma; Changcheng Zhou; Shuxia Wang
Journal:  Liver Int       Date:  2022-02-15       Impact factor: 8.754

5.  Hepatoprotective Effect of Oplopanax elatus Nakai Adventitious Roots Extract by Regulating CYP450 and PPAR Signaling Pathway.

Authors:  Xiao-Long Jiang; Pan-Yue Luo; Yan-Ying Zhou; Zhi-Hui Luo; Yue-Jun Hao; Ming-Zhi Fan; Xiao-Han Wu; Hao Gao; Hui-Chang Bi; Zhi-Bin Zhao; Mei-Lan Lian; Zhe-Xiong Lian
Journal:  Front Pharmacol       Date:  2022-05-02       Impact factor: 5.988

6.  MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types.

Authors:  Xiaolin Wang; Wonhyo Seo; Seol Hee Park; Yaojie Fu; Seonghwan Hwang; Robim M Rodrigues; Dechun Feng; Bin Gao; Yong He
Journal:  Int J Biol Sci       Date:  2021-03-11       Impact factor: 6.580

Review 7.  Epigenetics of alcohol-related liver diseases.

Authors:  Nawras W Habash; Tejasav S Sehrawat; Vijay H Shah; Sheng Cao
Journal:  JHEP Rep       Date:  2022-03-10

8.  Single-cell RNA-seq reveals transcriptional landscape and intratumor heterogenicity in gallbladder cancer liver metastasis microenvironment.

Authors:  Yigang Zhang; Wen-Hua You; Xiangyu Li; Peng Wang; Bowen Sha; Yuan Liang; Jiannan Qiu; Jinren Zhou; Haoran Hu; Ling Lu
Journal:  Ann Transl Med       Date:  2021-05

Review 9.  Crosstalk between Oxidative Stress and Inflammatory Liver Injury in the Pathogenesis of Alcoholic Liver Disease.

Authors:  Yoon Mee Yang; Ye Eun Cho; Seonghwan Hwang
Journal:  Int J Mol Sci       Date:  2022-01-11       Impact factor: 5.923

Review 10.  Inflammation and Fibrogenesis in MAFLD: Role of the Hepatic Immune System.

Authors:  Pietro Torre; Benedetta Maria Motta; Roberta Sciorio; Mario Masarone; Marcello Persico
Journal:  Front Med (Lausanne)       Date:  2021-12-09
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