Literature DB >> 3315740

Polyclonal B-cell activation after intravenous immunoglobulin therapy in idiopathic thrombocytopenic purpura--an anti-idiotype response?

A G Wangel1, M Lorenzetti, T Pettersson.   

Abstract

Polyclonal B cell activation occurred in 3 patients following treatment with intravenous immunoglobulin (i.v. Ig) for idiopathic thrombocytopenic purpura (ITP). The possibility that this may represent an anti-idiotype response and the hypothesis that prolonged remission of ITP may be induced by this mechanism are discussed.

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Year:  1987        PMID: 3315740     DOI: 10.1111/j.1600-0609.1987.tb00759.x

Source DB:  PubMed          Journal:  Eur J Haematol        ISSN: 0902-4441            Impact factor:   2.997


  2 in total

1.  Treatment of septic thrombocytopenia with immune globulin.

Authors:  E R Burns; V Lee; A Rubinstein
Journal:  J Clin Immunol       Date:  1991-11       Impact factor: 8.317

2.  The comparison of gammaglobulin to steroids in treating adult immune thrombocytopenia. An interim analysis.

Authors:  P Jacobs; L Wood
Journal:  Blut       Date:  1989-07
  2 in total

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