| Literature DB >> 3315462 |
Abstract
The process of transcription initiation requires both the recognition of a promoter site by RNA polymerase and the melting of a short stretch of DNA. In this review I discuss the properties of promoters that are relevant to sequence recognition and to the ability of the polymerase to act as a melting protein. The regulation of promoter activity is thus dependent on both factors interacting with RNA polymerase and so altering its affinity for promoter sites and also modulations of DNA structure.Entities:
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Year: 1987 PMID: 3315462 DOI: 10.3109/10409238709101483
Source DB: PubMed Journal: CRC Crit Rev Biochem ISSN: 0045-6411