Literature DB >> 33150883

17O NMR spectroscopy as a tool to study hydrogen bonding of cholesterol in lipid bilayers.

Lucy J Rowlands1, Adam Marks, John M Sanderson, Robert V Law.   

Abstract

Cholesterol is a crucial component of biological membranes and can interact with other membrane components through hydrogen bonding. NMR spectroscopy has been used previously to investigate this bonding, however this study represents the first 17O NMR spectroscopy study of isotopically enriched cholesterol. We demonstrate the 17O chemical shift is dependent on hydrogen bonding, providing a novel method for the study of cholesterol in bilayers.

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Year:  2020        PMID： 33150883     DOI： 10.1039/d0cc05466f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Detection of Water Molecules on the Radical Transfer Pathway of Ribonucleotide Reductase by 17O Electron-Nuclear Double Resonance Spectroscopy.

Authors:  Fabian Hecker; JoAnne Stubbe; Marina Bennati
Journal:  J Am Chem Soc       Date:  2021-05-06       Impact factor: 15.419

2.  Solid-state 17O NMR study of α-d-glucose: exploring new frontiers in isotopic labeling, sensitivity enhancement, and NMR crystallography.

Authors:  Jiahui Shen; Victor Terskikh; Jochem Struppe; Alia Hassan; Martine Monette; Ivan Hung; Zhehong Gan; Andreas Brinkmann; Gang Wu
Journal:  Chem Sci       Date:  2022-01-03       Impact factor: 9.825
  2 in total

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