Literature DB >> 3314991

On the rational design of renin inhibitors: X-ray studies of aspartic proteinases complexed with transition-state analogues.

T L Blundell1, J Cooper, S I Foundling, D M Jones, B Atrash, M Szelke.   

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Year:  1987        PMID： 3314991     DOI： 10.1021/bi00392a001

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


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  18 in total

1.  Analysis of crystal structures of aspartic proteinases: on the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymes.

Authors:  N S Andreeva; L D Rumsh
Journal:  Protein Sci       Date:  2001-12       Impact factor: 6.725

2.  X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.

Authors:  A L Swain; M M Miller; J Green; D H Rich; J Schneider; S B Kent; A Wlodawer
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

3.  The selectivity of statine-based inhibitors against various human aspartic proteinases.

Authors:  R A Jupp; B M Dunn; J W Jacobs; G Vlasuk; K E Arcuri; D F Veber; D S Perlow; L S Payne; J Boger; S de Laszlo
Journal:  Biochem J       Date:  1990-02-01       Impact factor: 3.857

Review 4.  Prediction of binding constants of protein ligands: a fast method for the prioritization of hits obtained from de novo design or 3D database search programs.

Authors:  H J Böhm
Journal:  J Comput Aided Mol Des       Date:  1998-07       Impact factor: 3.686

Review 5.  Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesis.

Authors:  K Ikuta; S Suzuki; H Horikoshi; T Mukai; R B Luftig
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

6.  On the use of LUDI to search the Fine Chemicals Directory for ligands of proteins of known three-dimensional structure.

Authors:  H J Böhm
Journal:  J Comput Aided Mol Des       Date:  1994-10       Impact factor: 3.686

7.  A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.

Authors:  D Bailey; J B Cooper
Journal:  Protein Sci       Date:  1994-11       Impact factor: 6.725

8.  Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.

Authors:  Hai Xu; Catherine Faber; Tomoaki Uchiki; Joseph Racca; Chris Dealwis
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-06       Impact factor: 11.205

Review 9.  Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease.

Authors:  Xiaoman Li; Lin Hong; Kathleen Coughlan; Liang Wang; Liu Cao; Jordan Tang
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2013-05-15       Impact factor: 3.848

10.  Exploration of subsite binding specificity of human cathepsin D through kinetics and rule-based molecular modeling.

Authors:  P E Scarborough; K Guruprasad; C Topham; G R Richo; G E Conner; T L Blundell; B M Dunn
Journal:  Protein Sci       Date:  1993-02       Impact factor: 6.725
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