Literature DB >> 33149314

Isoforms of GPCR proteins combine for diverse signalling.

Joshua C Snyder, Sudarshan Rajagopal.   

Abstract

Keywords:  Biochemistry

Mesh：

Substances：

Year:  2020        PMID： 33149314     DOI： 10.1038/d41586-020-03001-0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  15 in total

Review 1.  Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors.

Authors:  Craig W Lindsley; Kyle A Emmitte; Corey R Hopkins; Thomas M Bridges; Karen J Gregory; Colleen M Niswender; P Jeffrey Conn
Journal:  Chem Rev       Date:  2016-02-16       Impact factor: 60.622

2.  β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors.

Authors:  Lauren M Slosky; Yushi Bai; Krisztian Toth; Caroline Ray; Lauren K Rochelle; Alexandra Badea; Rahul Chandrasekhar; Vladimir M Pogorelov; Dennis M Abraham; Namratha Atluri; Satyamaheshwar Peddibhotla; Michael P Hedrick; Paul Hershberger; Patrick Maloney; Hong Yuan; Zibo Li; William C Wetsel; Anthony B Pinkerton; Lawrence S Barak; Marc G Caron
Journal:  Cell       Date:  2020-05-28       Impact factor: 41.582

Review 3.  Signalling bias in new drug discovery: detection, quantification and therapeutic impact.

Authors:  Terry Kenakin; Arthur Christopoulos
Journal:  Nat Rev Drug Discov       Date:  2012-02-15       Impact factor: 84.694

Review 4.  Biased signalling: from simple switches to allosteric microprocessors.

Authors:  Jeffrey S Smith; Robert J Lefkowitz; Sudarshan Rajagopal
Journal:  Nat Rev Drug Discov       Date:  2018-01-05       Impact factor: 84.694

5.  C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways.

Authors:  Jeffrey S Smith; Priya Alagesan; Nimit K Desai; Thomas F Pack; Jiao-Hui Wu; Asuka Inoue; Neil J Freedman; Sudarshan Rajagopal
Journal:  Mol Pharmacol       Date:  2017-05-30       Impact factor: 4.436

6.  Isoform-specific uncoupling of the D2 dopamine receptors subtypes.

Authors:  Ryan T Kendall; Susan E Senogles
Journal:  Neuropharmacology       Date:  2010-10-01       Impact factor: 5.250

7.  Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy.

Authors:  Ségolène Galandrin; Michel Bouvier
Journal:  Mol Pharmacol       Date:  2006-08-10       Impact factor: 4.436

8.  The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.

Authors:  Robert Fredriksson; Malin C Lagerström; Lars-Gustav Lundin; Helgi B Schiöth
Journal:  Mol Pharmacol       Date:  2003-06       Impact factor: 4.436

Review 9.  Trends in GPCR drug discovery: new agents, targets and indications.

Authors:  Alexander S Hauser; Misty M Attwood; Mathias Rask-Andersen; Helgi B Schiöth; David E Gloriam
Journal:  Nat Rev Drug Discov       Date:  2017-10-27       Impact factor: 84.694

Review 10.  GPCRdb: the G protein-coupled receptor database - an introduction.

Authors:  C Munk; V Isberg; S Mordalski; K Harpsøe; K Rataj; A S Hauser; P Kolb; A J Bojarski; G Vriend; D E Gloriam
Journal:  Br J Pharmacol       Date:  2016-06-03       Impact factor: 8.739
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