Qun Chen1, Edward J Lesnefsky2. 1. Departments of Internal Medicine, Cardiology, Pauley Heart Center, Richmond, Virginia. 2. Departments of Internal Medicine, Cardiology, Pauley Heart Center, Richmond, Virginia; Biochemistry, and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia; Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia; Medical Service of the McGuire Veterans Affairs Medical Center, Richmond, Virginia. Electronic address: edward.lesnefsky@va.gov.