Literature DB >> 3314794

Local recurrence in adult soft-tissue sarcoma. A randomized trial of brachytherapy.

M F Brennan1, B Hilaris, M H Shiu, J Lane, G Magill, C Friedrich, S I Hajdu.   

Abstract

We conducted a prospective randomized study of the benefit of adjuvant radiation therapy delivered by the brachytherapy technique in 117 adult patients who had soft-tissue sarcoma that was on an extremity or superficially localized to the trunk. A significant decrease in local recurrence was demonstrated in the patients receiving brachytherapy. The benefit did not appear to be due to any maldistribution in the known prognostic factors of size, site, depth, presentation with recurrence, or histologic grade. The decrease in local recurrence appears to be due to the decreased local recurrence in high-grade sarcomas. Survival differences were not identified, and accrual and follow-up were continued.

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Year:  1987        PMID： 3314794     DOI： 10.1001/archsurg.1987.01400230075014

Source DB:  PubMed          Journal:  Arch Surg        ISSN： 0004-0010


  32 in total

1.  Multifactorial analysis of survival in primary extremity liposarcoma.

Authors:  H R Chang; J Gaynor; C Tan; S I Hajdu; M F Brennan
Journal:  World J Surg       Date:  1990 Sep-Oct       Impact factor: 3.352

2.  Do surgical margin and local recurrence influence survival in soft tissue sarcomas?

Authors:  Eduardo N Novais; Bahtiyar Demiralp; Joseph Alderete; Melissa C Larson; Peter S Rose; Franklin H Sim
Journal:  Clin Orthop Relat Res       Date:  2010-11       Impact factor: 4.176

3.  Wound complications after resection and immediate postoperative brachytherapy in the management of soft-tissue sarcomas.

Authors:  R R Dalton; R M Lanciano; J P Hoffman; B L Eisenberg
Journal:  Ann Surg Oncol       Date:  1996-01       Impact factor: 5.344

4.  Efficacy of adjuvant radiation therapy in the treatment of soft tissue sarcoma of the extremity: 20-year follow-up of a randomized prospective trial.

Authors:  Joal D Beane; James C Yang; Donald White; Seth M Steinberg; Steven A Rosenberg; Udo Rudloff
Journal:  Ann Surg Oncol       Date:  2014-04-23       Impact factor: 5.344

5.  Prognostic factors predictive of survival and local recurrence for extremity soft tissue sarcoma.

Authors:  S Singer; J M Corson; R Gonin; B Labow; T J Eberlein
Journal:  Ann Surg       Date:  1994-02       Impact factor: 12.969

6.  The enigma of myxofibrosarcoma of the extremity.

Authors:  Robert W Mutter; Samuel Singer; Zhigang Zhang; Murray F Brennan; Kaled M Alektiar
Journal:  Cancer       Date:  2011-06-29       Impact factor: 6.860

7.  Comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity.

Authors:  W C Williard; S I Hajdu; E S Casper; M F Brennan
Journal:  Ann Surg       Date:  1992-03       Impact factor: 12.969

8.  Implications of staged reconstruction and adjuvant brachytherapy in the treatment of recurrent soft tissue sarcoma.

Authors:  Arash O Naghavi; Ricardo J Gonzalez; Jacob G Scott; John E Mullinax; Yazan A Abuodeh; Youngchul Kim; Odion Binitie; Kamran A Ahmed; Marilyn M Bui; Amarjit S Saini; Jonathan S Zager; Matthew C Biagioli; Douglas Letson; Louis B Harrison; Daniel C Fernandez
Journal:  Brachytherapy       Date:  2016-05-12       Impact factor: 2.362

9.  Prognostic factors predictive of survival for truncal and retroperitoneal soft-tissue sarcoma.

Authors:  S Singer; J M Corson; G D Demetri; E A Healey; K Marcus; T J Eberlein
Journal:  Ann Surg       Date:  1995-02       Impact factor: 12.969

10.  Comparison of charges related to radiotherapy for soft-tissue sarcomas treated by preoperative external-beam irradiation versus interstitial implantation.

Authors:  N A Janjan; A W Yasko; G P Reece; M J Miller; J A Murray; M I Ross; M M Romsdahl; M J Oswald; T G Ochran; R E Pollock
Journal:  Ann Surg Oncol       Date:  1994-09       Impact factor: 5.344
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