Literature DB >> 33145902

Navigating Diagnostic and Treatment Decisions in Non-Small Cell Lung Cancer: Expert Commentary on the Multidisciplinary Team Approach.

Sanjay Popat1,2, Neal Navani3, Keith M Kerr4, Egbert F Smit5, Timothy J P Batchelor6, Paul Van Schil7, Suresh Senan8, Fiona McDonald1,2.   

Abstract

Non-small cell lung cancer (NSCLC) accounts for approximately one in five cancer-related deaths, and management requires increasingly complex decision making by health care professionals. Many centers have therefore adopted a multidisciplinary approach to patient care, using the expertise of various specialists to provide the best evidence-based, personalized treatment. However, increasingly complex disease staging, as well as expanded biomarker testing and multimodality management algorithms with novel therapeutics, have driven the need for multifaceted, collaborative decision making to optimally guide the overall treatment process. To keep up with the rapidly evolving treatment landscape, national-level guidelines have been introduced to standardize patient pathways and ensure prompt diagnosis and treatment. Such strategies depend on efficient and effective communication between relevant multidisciplinary team members and have both improved adherence to treatment guidelines and extended patient survival. This article highlights the value of a multidisciplinary approach to diagnosis and staging, treatment decision making, and adverse event management in NSCLC. IMPLICATIONS FOR PRACTICE: This review highlights the value of a multidisciplinary approach to the diagnosis and staging of non-small cell lung cancer (NSCLC) and makes practical suggestions as to how multidisciplinary teams (MDTs) can be best deployed at individual stages of the disease to improve patient outcomes and effectively manage common adverse events. The authors discuss how a collaborative approach, appropriately leveraging the diverse expertise of NSCLC MDT members (including specialist radiation and medical oncologists, chest physicians, pathologists, pulmonologists, surgeons, and nursing staff) can continue to ensure optimal per-patient decision making as treatment options become ever more specialized in the era of biomarker-driven therapeutic strategies.
© 2020 The Authors. The Oncologist published by Wiley Periodicals LLC on behalf of AlphaMed Press.

Entities:  

Keywords:  Decision making; Lung cancer; Multidisciplinary; Non-small cell lung cancer; Treatment guidelines

Mesh:

Year:  2020        PMID: 33145902      PMCID: PMC7873339          DOI: 10.1002/onco.13586

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159            Impact factor:   5.837


  69 in total

1.  Magnetic resonance imaging for staging of non-small-cell lung cancer-technical advances and unmet needs.

Authors:  Gregor Sommer; Bram Stieltjes
Journal:  J Thorac Dis       Date:  2015-07       Impact factor: 2.895

2.  Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  D Planchard; S Popat; K Kerr; S Novello; E F Smit; C Faivre-Finn; T S Mok; M Reck; P E Van Schil; M D Hellmann; S Peters
Journal:  Ann Oncol       Date:  2018-10-01       Impact factor: 32.976

3.  Survival Comparison in Patients with Stage IV Lung Cancer in Academic versus Community Centers in the United States.

Authors:  Sendhilnathan Ramalingam; Michaela A Dinan; Jeffrey Crawford
Journal:  J Thorac Oncol       Date:  2018-10-09       Impact factor: 15.609

4.  Real-World Treatment Patterns, Overall Survival, and Occurrence and Costs of Adverse Events Associated With Second-Line Therapies for Medicare Patients With Advanced Non-Small-Cell Lung Cancer.

Authors:  Ashwini Arunachalam; Haojie Li; Marisa A Bittoni; Ramon Camacho; Xiting Cao; Yichen Zhong; Gregory M Lubiniecki; David P Carbone
Journal:  Clin Lung Cancer       Date:  2018-06-06       Impact factor: 4.785

5.  Management of Multifocal Lung Cancer: Results of a Survey.

Authors:  Konstantinos Leventakos; Tobias Peikert; David E Midthun; Julian R Molina; Shanda Blackmon; Francis C Nichols; Yolanda I Garces; Christopher L Hallemeier; Stephen J Murphy; George Vasmatzis; Sarah L Kratz; William P Holland; Charles F Thomas; John J Mullon; K Robert Shen; Stephen D Cassivi; Randolph S Marks; Marie Christine Aubry; Alex A Adjei; Ping Yang; Mark S Allen; Eric S Edell; Dennis Wigle; Aaron S Mansfield
Journal:  J Thorac Oncol       Date:  2017-06-03       Impact factor: 15.609

6.  Outcomes with durvalumab by tumour PD-L1 expression in unresectable, stage III non-small-cell lung cancer in the PACIFIC trial.

Authors:  L Paz-Ares; A Spira; D Raben; D Planchard; B C Cho; M Özgüroğlu; D Daniel; A Villegas; D Vicente; R Hui; S Murakami; D Spigel; S Senan; C J Langer; B A Perez; A-M Boothman; H Broadhurst; C Wadsworth; P A Dennis; S J Antonia; C Faivre-Finn
Journal:  Ann Oncol       Date:  2020-03-21       Impact factor: 32.976

7.  Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis.

Authors:  Yucai Wang; Shouhao Zhou; Fang Yang; Xinyue Qi; Xin Wang; Xiaoxiang Guan; Chan Shen; Narjust Duma; Jesus Vera Aguilera; Ashish Chintakuntlawar; Katharine A Price; Julian R Molina; Lance C Pagliaro; Thorvardur R Halfdanarson; Axel Grothey; Svetomir N Markovic; Grzegorz S Nowakowski; Stephen M Ansell; Michael L Wang
Journal:  JAMA Oncol       Date:  2019-07-01       Impact factor: 31.777

8.  Lung cancer treatment rates and the role of the lung cancer nurse specialist: a qualitative study.

Authors:  Angela Mary Tod; Judy Redman; Ann McDonnell; Diana Borthwick; John White
Journal:  BMJ Open       Date:  2015-12-18       Impact factor: 2.692

Review 9.  Management of adverse events related to checkpoint inhibition therapy.

Authors:  Jakob Daniel Rudzki
Journal:  Memo       Date:  2018-06-12

10.  Pan-Asian adapted ESMO Clinical Practice Guidelines for the management of patients with locally-advanced unresectable non-small-cell lung cancer: a KSMO-ESMO initiative endorsed by CSCO, ISMPO, JSMO, MOS, SSO and TOS.

Authors:  K Park; J Vansteenkiste; K H Lee; G Pentheroudakis; C Zhou; K Prabhash; T Seto; P J Voon; D S W Tan; J C H Yang; J Wang; K Govind Babu; Y Nakayama; A Alip; K L M Chua; J C-H Cheng; S Senan; Y C Ahn; T-Y Kim; H K Ahn; S Peters; T Yoshino; J-Y Douillard
Journal:  Ann Oncol       Date:  2019-12-20       Impact factor: 32.976

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  5 in total

Review 1.  Virtual Multidisciplinary Tumor Boards: A Narrative Review Focused on Lung Cancer.

Authors:  Vittorio Gebbia; Aurelia Guarini; Dario Piazza; Alessandro Bertani; Massimiliano Spada; Francesco Verderame; Concetta Sergi; Enrico Potenza; Ivan Fazio; Livio Blasi; Alba La Sala; Gianluca Mortillaro; Elena Roz; Roberto Marchese; Maurizio Chiarenza; Hector Soto-Parra; Maria Rosaria Valerio; Giuseppe Agneta; Carmela Amato; Helga Lipari; Sergio Baldari; Francesco Ferraù; Alfio Di Grazia; Gianfranco Mancuso; Sergio Rizzo; Alberto Firenze
Journal:  Pulm Ther       Date:  2021-06-04

2.  Effectiveness of Immune Checkpoint Inhibition vs Chemotherapy in Combination With Radiation Therapy Among Patients With Non-Small Cell Lung Cancer and Brain Metastasis Undergoing Neurosurgical Resection.

Authors:  David Wasilewski; Josefine Radke; Ran Xu; Matthias Raspe; Anna Trelinska-Finger; Tizian Rosenstock; Paul Poeser; Elisa Schumann; Judith Lindner; Frank Heppner; David Kaul; Norbert Suttorp; Peter Vajkoczy; Nikolaj Frost; Julia Onken
Journal:  JAMA Netw Open       Date:  2022-04-01

3.  Relationship between Treatment Plan Dosimetry, Toxicity, and Survival following Intensity-Modulated Radiotherapy, with or without Chemotherapy, for Stage III Inoperable Non-Small Cell Lung Cancer.

Authors:  Isabel F Remmerts de Vries; Merle I Ronden; Idris Bahce; Femke O B Spoelstra; Patricia F De Haan; Cornelis J A Haasbeek; Birgit I Lissenberg-Witte; Ben J Slotman; Max Dahele; Wilko F A R Verbakel
Journal:  Cancers (Basel)       Date:  2021-11-25       Impact factor: 6.639

4.  Real-World Perspectives From Surgeons and Oncologists on Resectability Definition and Multidisciplinary Team Discussion of Stage III NSCLC in People's Republic of China, Hong Kong, and Macau: A Physician Survey.

Authors:  Victor Ho-Fun Lee; Joseph Siu Kie Au; Ju-Wei Mu; Guangli Xiao; Fiona Mei Ying Lim; Hon Chi Suen; Kam Hung Wong
Journal:  JTO Clin Res Rep       Date:  2022-03-19

5.  Effect of Nursing Model Based on Rosenthal Effect on Self-Efficacy and Cognition of Life Meaning in Patients with Non-Small-Cell Lung Cancer.

Authors:  Linghua Mao; Huaqin Lu; Yangyang Lu
Journal:  Emerg Med Int       Date:  2022-08-08       Impact factor: 1.621

  5 in total

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