| Literature DB >> 33143625 |
Kelu Li1, Zichao Chen2, Yonggang Zhang3, Xinglong Yang1.
Abstract
Neurodegenerative diseases are caused by progressive lesions or loss of specific nerve cells, which endanger human health. However, the mechanism by which neurodegeneration manifests remains unclear. Proteomics can shed light on this question as well as help establish diagnostic standards and discover new drug targets. The power of proteomics for understanding neurodegenerative diseases has increased substantially with the application of iTRAQ and TMT labeling techniques. This review focuses on progress in these labeling techniques and their applications in neurodegeneration research. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Neurodegenerative diseases; TMT; iTRAQ; neuro-imaging; proteomics; quantitative neuroproteomics
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Year: 2020 PMID： 33143625 DOI： 10.2174/1389203721666201103085704
Source DB: PubMed Journal: Curr Protein Pept Sci ISSN： 1389-2037 Impact factor: 3.272