Tomorrow's hepatitis B vaccines. Arie Zuckerman discusses hepatitis B vaccines of the future and the impact of AIDS on immunization.

Recombinant hepatitis B vaccines produced in yeast and in mammalian cells are the first of future vaccines against this important public health problem. Hybrid virus vaccines and the use of baculoviruses for expression of hepatitis B antigens in insect cell cultures will follow shortly and chemically synthetic vaccines are under development. The impact of AIDS on future immunization programmes should be considered.