| Literature DB >> 33140748 |
Jonas Bucevičius1, Tanja Gilat1, GraŽvydas Lukinavičius1.
Abstract
Herein we present DNA probes composed of Hoechst 33258 and spontaneously blinking far-red hydroxymethyl silicon-rhodamine (HMSiR). The best performing probe, 5-HMSiR-Hoechst, contains the 5'-regioisomer, shows ∼400-fold fluorescence increase upon DNA binding and is compatible with wash-free single molecule localization and 3D stimulated emission depletion microscopy of chromatin nanostructures in living cells.Entities:
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Year: 2020 PMID: 33140748 DOI: 10.1039/d0cc06759h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222