Mamta Agarwal1, Aleksandra Radosavljevic2, Gazal Patnaik3, Ekta Rishi4, Francesco Pichi5,6. 1. Uveitis & Cornea Services, Sankara Nethralaya, Chennai, India. 2. Department of Ophthalmology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia. 3. Uveitis Services, Sankara Nethralaya, Chennai, India. 4. Vitreoretinal Services, Sankara Nethralaya, Chennai, India. 5. Cleveland Clinic Abu Dhabi, Eye Institute, Abu Dhabi, United Arab Emirates. 6. Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Abstract
PURPOSE: To describe the role of optical coherence tomography (OCT) in detecting subclinical choroidal inflammation and early diagnosis of macular complications in chronic Vogt-Koyanagi-Harada (VKH) disease with sunset glow fundus. METHODS: Retrospective observational study. Clinical features, OCT images, treatment, and visual outcome were analyzed. RESULTS: Fourteen patients (9 females and 5 males) were included in the study. Mean age was 39 years (range 7-67 years). Mean duration of disease was 5.25 years (range 1-15 years). Anterior uveitis was seen in 14 eyes (52%). Fundus examination showed sunset glow fundus in all patients with no obvious macular pathology. OCT showed macular edema in 16 eyes (59%), choroidal neovascular membrane in 8 eyes (30%), and macular hole in 3 eyes (11%). CONCLUSION: OCT should be regularly used to detect subclinical inflammation and early macular complications in chronic VKH disease where sunset glow fundus may delay the clinical diagnosis thus causing permanent damage.
PURPOSE: To describe the role of optical coherence tomography (OCT) in detecting subclinical choroidal inflammation and early diagnosis of macular complications in chronic Vogt-Koyanagi-Harada (VKH) disease with sunset glow fundus. METHODS: Retrospective observational study. Clinical features, OCT images, treatment, and visual outcome were analyzed. RESULTS: Fourteen patients (9 females and 5 males) were included in the study. Mean age was 39 years (range 7-67 years). Mean duration of disease was 5.25 years (range 1-15 years). Anterior uveitis was seen in 14 eyes (52%). Fundus examination showed sunset glow fundus in all patients with no obvious macular pathology. OCT showed macular edema in 16 eyes (59%), choroidal neovascular membrane in 8 eyes (30%), and macular hole in 3 eyes (11%). CONCLUSION: OCT should be regularly used to detect subclinical inflammation and early macular complications in chronic VKH disease where sunset glow fundus may delay the clinical diagnosis thus causing permanent damage.