BACKGROUND: Epidural corticosteroid injection is one of the most common non-surgical procedures for lumbosacral radicular pain. OBJECTIVE: To assess efficacy and safety of epidural corticosteroid injections compared with placebo injections in patients with lumbosacral radicular pain. METHODS: A summary and commentary of a Cochrane Review by Oliveira et al. RESULTS: 25 studies with a total of 2740 participants were included in the review. Moderate quality evidence pointed out a small effect on leg pain at immediate and short-term follow-up and on disability at short-term and intermediate follow-up. Adverse events were not different between corticosteroid and placebo injections. CONCLUSIONS: Epidural corticosteroid injection is slightly more effective than placebo for leg pain and disability at short-term follow up. Clinicians and patients however should be informed of the small effect size of the treatment.
BACKGROUND: Epidural corticosteroid injection is one of the most common non-surgical procedures for lumbosacral radicular pain. OBJECTIVE: To assess efficacy and safety of epidural corticosteroid injections compared with placebo injections in patients with lumbosacral radicular pain. METHODS: A summary and commentary of a Cochrane Review by Oliveira et al. RESULTS: 25 studies with a total of 2740 participants were included in the review. Moderate quality evidence pointed out a small effect on leg pain at immediate and short-term follow-up and on disability at short-term and intermediate follow-up. Adverse events were not different between corticosteroid and placebo injections. CONCLUSIONS: Epidural corticosteroid injection is slightly more effective than placebo for leg pain and disability at short-term follow up. Clinicians and patients however should be informed of the small effect size of the treatment.