Literature DB >> 33134206

Severe scarlet fever in a child with Down syndrome - a case report.

Halyna Pavlyshyn1, Ivanna Horishna2, Iryna Sarapuk3.   

Abstract

INTRODUCTION: Scarlet fever is an acute infectious disease that is characterized by development of characteristic pin-point exanthema in a patient with signs of streptococcal pharyngitis and tonsillitis. Nowadays, due to effective antibacterial treatment, severe complicated cases of scarlet fever are occasionally rare. Because of immunity particularities, patients with Down syndrome are predisposed to bacterial respiratory diseases (and scarlet fever among them), that usually have prolonged complicated course. CASE REPORT: A clinical case of scarlet fever in a patient with Down syndrome was analyzed. The disease had a severe course with a specific skin syndrome and was complicated by pneumonia. Hospitalization and adequate treatment of the patient led to his complete recovery despite late initiation of antibacterial medicine. DISCUSSION: A long severe complicated course of the disease in the presented case was caused by combination of the late initiation of antibacterial treatment and the patient's personal particularities of reactivity.
CONCLUSIONS: Patients with Down syndrome should be adequately monitored by family doctors in case of pharyngitis with early testing for group A hemolytic Streptococcus infection and administration of the correct antibacterial treatment, if the test is positive. GERMS.

Entities:  

Keywords:  Down syndrome; Scarlet fever; children; complications

Year:  2020        PMID: 33134206      PMCID: PMC7572208          DOI: 10.18683/germs.2020.1215

Source DB:  PubMed          Journal:  Germs        ISSN: 2248-2997


  10 in total

1.  Defective B-cell memory in patients with Down syndrome.

Authors:  Ruud H J Verstegen; Gertjan J Driessen; Sophinus J W Bartol; Carel J M van Noesel; Louis Boon; Mirjam van der Burg; Jacques J M van Dongen; Esther de Vries; Menno C van Zelm
Journal:  J Allergy Clin Immunol       Date:  2014-08-23       Impact factor: 10.793

2.  Down syndrome and streptococcus group A disease in hospitalized children.

Authors:  Orli Megged; Yechiel Schlesinger
Journal:  Acta Paediatr       Date:  2009-12-09       Impact factor: 2.299

3.  [Recurrent scarlet fever: A common entity].

Authors:  Bárbara de Dios Javierre; María García Ventura; Marta Arrudi Moreno; César García Vera
Journal:  An Pediatr (Barc)       Date:  2017-02-14       Impact factor: 1.500

4.  A 12 year outbreak of scarlet fever in Singapore.

Authors:  Chee Fu Yung; Koh Cheng Thoon
Journal:  Lancet Infect Dis       Date:  2018-09       Impact factor: 25.071

5.  Constantly high incidence of scarlet fever in Germany.

Authors:  Stefan O Brockmann; Linda Eichner; Martin Eichner
Journal:  Lancet Infect Dis       Date:  2018-05       Impact factor: 25.071

6.  Scarlet fever in Poland in 2014

Authors:  Ewa Staszewska-Jakubik; Mirosław P Czarkowski; Barbara Kondej
Journal:  Przegl Epidemiol       Date:  2016

Review 7.  Respiratory problems in children with Down syndrome.

Authors:  Chetan Pandit; Dominic A Fitzgerald
Journal:  J Paediatr Child Health       Date:  2011-04-29       Impact factor: 1.954

8.  Quantitative, Phenotypical, and Functional Characterization of Cellular Immunity in Children and Adolescents With Down Syndrome.

Authors:  Justine Schoch; Tilman R Rohrer; Michael Kaestner; Hashim Abdul-Khaliq; Ludwig Gortner; Urban Sester; Martina Sester; Tina Schmidt
Journal:  J Infect Dis       Date:  2017-05-15       Impact factor: 5.226

9.  Scarlet fever is caused by a limited number of Streptococcus pyogenes lineages and is associated with the exotoxin genes ssa, speA and speC.

Authors:  Catarina Silva-Costa; Joao A Carriço; Mario Ramirez; Jose Melo-Cristino
Journal:  Pediatr Infect Dis J       Date:  2014-03       Impact factor: 2.129

10.  Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America.

Authors:  Stanford T Shulman; Alan L Bisno; Herbert W Clegg; Michael A Gerber; Edward L Kaplan; Grace Lee; Judith M Martin; Chris Van Beneden
Journal:  Clin Infect Dis       Date:  2012-09-09       Impact factor: 9.079

  10 in total

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