Literature DB >> 33133739

High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot.

Regina Grigolli Cesar1, Bibiane Ramos Pinheiro Bispo1, Priscilla Helena Costa Alves Felix1, Maria Carolina Caparica Modolo1, Andreia Aparecida Freitas Souza1, Nelson K Horigoshi1, Alexandre T Rotta2.   

Abstract

We conducted a randomized controlled pilot study in infants with critical bronchiolitis ( n  = 63) comparing high-flow nasal cannula (HFNC, n  = 35) to continuous positive airway pressure (CPAP, n  = 28). The primary outcome was treatment failure, defined as the need for bilevel positive pressure ventilation or endotracheal intubation. Treatment failure occurred in 10 patients (35.7%) in the CPAP group and 13 patients (37.1%) in the HFNC group ( p  = 0.88). Pediatric intensive care unit length of stay was similar between the CPAP and HFNC groups (5 [4-7] days and 5 [4-8] days, p  = 0.46, respectively). In this pilot study, treatment with HFNC resulted in a rate of treatment failure similar to CPAP. Thieme. All rights reserved.

Entities:  

Keywords:  acute respiratory failure; bronchiolitis; continuous positive airway pressure; high-flow nasal cannula; infants; respiratory syncytial virus

Year:  2020        PMID： 33133739      PMCID： PMC7588294          DOI： 10.1055/s-0040-1709656

Source DB:  PubMed          Journal:  J Pediatr Intensive Care        ISSN： 2146-4626


  33 in total

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3.  High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study).

Authors:  Christophe Milési; Sandrine Essouri; Robin Pouyau; Jean-Michel Liet; Mickael Afanetti; Aurélie Portefaix; Julien Baleine; Sabine Durand; Clémentine Combes; Aymeric Douillard; Gilles Cambonie
Journal:  Intensive Care Med       Date:  2017-01-26       Impact factor: 17.440

4.  Outcomes of Children With Bronchiolitis Treated With High-Flow Nasal Cannula or Noninvasive Positive Pressure Ventilation.

Authors:  Jason A Clayton; Bryan McKee; Katherine N Slain; Alexandre T Rotta; Steven L Shein
Journal:  Pediatr Crit Care Med       Date:  2019-02       Impact factor: 3.624

5.  Temporal Trends of Respiratory Syncytial Virus-Associated Hospital and ICU Admissions Across the United States.

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7.  A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2).

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Journal:  Intensive Care Med       Date:  2018-10-21       Impact factor: 17.440

8.  The burden of respiratory syncytial virus infection in young children.

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9.  Comparative Study between Noninvasive Continuous Positive Airway Pressure and Hot Humidified High-flow Nasal Cannulae as a Mode of Respiratory Support in Infants with Acute Bronchiolitis in Pediatric Intensive Care Unit of a Tertiary Care Hospital.

Authors:  Mihir Sarkar; Rajasree Sinha; Satyabrata Roychowdhoury; Sobhanman Mukhopadhyay; Pramit Ghosh; Kalpana Dutta; Shibarjun Ghosh
Journal:  Indian J Crit Care Med       Date:  2018-02

10.  Improved clinical and economic outcomes in severe bronchiolitis with pre-emptive nCPAP ventilatory strategy.

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Journal:  Intensive Care Med       Date:  2013-10-25       Impact factor: 17.440
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  6 in total

1.  Response from the Authors.

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Journal:  Eur J Pediatr       Date:  2022-09-21       Impact factor: 3.860

3.  Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units: A Randomized Clinical Trial.

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Journal:  JAMA       Date:  2022-07-12       Impact factor: 157.335

4.  Truth Has Nothing to Do with the Conclusion, and Everything to Do with the Methodology.

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5.  Non-Invasive Ventilation Strategies in Children With Acute Lower Respiratory Infection: A Systematic Review and Bayesian Network Meta-Analysis.

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6.  Comparison of high flow nasal cannula and non-invasive positive pressure ventilation in children with bronchiolitis: A meta-analysis of randomized controlled trials.

Authors:  Zhaoshuang Zhong; Long Zhao; Yan Zhao; Shuyue Xia
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  6 in total

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