Literature DB >> 3313275

The nucleotide sequence of the PRI1 gene related to DNA primase in Saccharomyces cerevisiae.

P Plevani1, S Francesconi, G Lucchini.   

Abstract

The PRI1 gene of Saccharomyces cerevisiae encodes for the p48 polypeptide of DNA primase. We have determined the nucleotide sequence of a 1,965 bp DNA fragment containing the PRI1 locus. The entire coding sequence of the gene lies within an open reading frame, and there are 409 amino acids in the single polypeptide protein if translation is assumed to start at the first ATG in this frame. The 5' and 3' end-points of PRI1 mRNA have been determined by S1 mapping and primer extension analysis. The primary structure and the codon usage of PRI1 suggest that this essential gene is poorly expressed in yeast cells.

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Year:  1987        PMID: 3313275      PMCID: PMC306321          DOI: 10.1093/nar/15.19.7975

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  32 in total

1.  The nucleotide sequence of the RAD3 gene of Saccharomyces cerevisiae: a potential adenine nucleotide binding amino acid sequence and a nonessential acidic carboxyl terminal region.

Authors:  P Reynolds; D R Higgins; L Prakash; S Prakash
Journal:  Nucleic Acids Res       Date:  1985-04-11       Impact factor: 16.971

Review 2.  Eukaryotic DNA replication.

Authors:  J L Campbell
Journal:  Annu Rev Biochem       Date:  1986       Impact factor: 23.643

3.  Specific-primer-directed DNA sequencing.

Authors:  E C Strauss; J A Kobori; G Siu; L E Hood
Journal:  Anal Biochem       Date:  1986-04       Impact factor: 3.365

4.  Bifunctional messenger RNAs in eukaryotes.

Authors:  M Kozak
Journal:  Cell       Date:  1986-11-21       Impact factor: 41.582

5.  Dideoxy sequencing method using denatured plasmid templates.

Authors:  M Hattori; Y Sakaki
Journal:  Anal Biochem       Date:  1986-02-01       Impact factor: 3.365

6.  Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes.

Authors:  P M Sharp; T M Tuohy; K R Mosurski
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971

7.  Isolation of the gene encoding yeast DNA polymerase I.

Authors:  L M Johnson; M Snyder; L M Chang; R W Davis; J L Campbell
Journal:  Cell       Date:  1985-11       Impact factor: 41.582

8.  The complete nucleotide sequence of the structural gene TOP2 of yeast DNA topoisomerase II.

Authors:  G Giaever; R Lynn; T Goto; J C Wang
Journal:  J Biol Chem       Date:  1986-09-25       Impact factor: 5.157

9.  The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae.

Authors:  G Natsoulis; F Hilger; G R Fink
Journal:  Cell       Date:  1986-07-18       Impact factor: 41.582

10.  Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.

Authors:  M Kozak
Journal:  Cell       Date:  1986-01-31       Impact factor: 41.582

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  12 in total

Review 1.  Yeast chromosome replication and segregation.

Authors:  C S Newlon
Journal:  Microbiol Rev       Date:  1988-12

2.  DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases.

Authors:  A Pizzagalli; P Valsasnini; P Plevani; G Lucchini
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

3.  A cell cycle-responsive transcriptional control element and a negative control element in the gene encoding DNA polymerase alpha in Saccharomyces cerevisiae.

Authors:  C B Gordon; J L Campbell
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

4.  Positive cis-acting regulatory sequences mediate proper control of POL1 transcription in Saccharomyces cerevisiae.

Authors:  A Pizzagalli; S Piatti; D Derossi; I Gander; P Plevani; G Lucchini
Journal:  Curr Genet       Date:  1992-03       Impact factor: 3.886

5.  Mutations in conserved yeast DNA primase domains impair DNA replication in vivo.

Authors:  S Francesconi; M P Longhese; A Piseri; C Santocanale; G Lucchini; P Plevani
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-01       Impact factor: 11.205

6.  Conditional mutations in the yeast DNA primase genes affect different aspects of DNA metabolism and interactions in the DNA polymerase alpha-primase complex.

Authors:  M P Longhese; L Jovine; P Plevani; G Lucchini
Journal:  Genetics       Date:  1993-02       Impact factor: 4.562

7.  Identification and purification of a factor that binds to the Mlu I cell cycle box of yeast DNA replication genes.

Authors:  R Verma; A Patapoutian; C B Gordon; J L Campbell
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-15       Impact factor: 11.205

8.  The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.

Authors:  M Foiani; F Marini; D Gamba; G Lucchini; P Plevani
Journal:  Mol Cell Biol       Date:  1994-02       Impact factor: 4.272

9.  DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells.

Authors:  J Syväoja; S Suomensaari; C Nishida; J S Goldsmith; G S Chui; S Jain; S Linn
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

10.  A single essential gene, PRI2, encodes the large subunit of DNA primase in Saccharomyces cerevisiae.

Authors:  M Foiani; C Santocanale; P Plevani; G Lucchini
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

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