Leonardo Solaini1,2, Davide Cavaliere2, Valeria Fico3, Marco Milone4, Stefano De Pascale5, Jacopo Desiderio6, Giulia Vitali2, Amilcare Parisi6, Uberto Fumagalli Romario5, Giovanni Domenico De Palma4, Domenico D'Ugo3, Giorgio Ercolani1,2. 1. Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy. 2. General and Oncologic Surgery, Morgagni Pierantoni Hospital, Ausl Romagna, Forlì, Italy. 3. General Surgery Unit, Department of Surgery, "A. Gemelli" University Hospital, Catholic University of Rome, Rome, Italy. 4. Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy. 5. Digestive Surgery, European Institute of Oncology IRCCS, Milan, Italy. 6. Department of Digestive Surgery and Liver Unit, Santa Maria Hospital, Terni, Italy.
Abstract
PURPOSE: To present the outcomes of gastric gastrointestinal stromal tumour (GIST) resection from five Italian centres, focussing the analysis on the comparison among open (OG), laparoscopic (LG) and robotic (RG) approaches. METHODS: All consecutive gastric wedge resections for GIST between 2009 and 2019 were included. RESULTS: In total 101 (OG = 14, LG = 63 and RG = 24) were included. No differences were seen in the preoperative characteristics among the groups. Robotic procedures were longer (RG 180 min vs. LG 100 vs. OG 110; p < 0.0001). Time-to-first flatus and length of hospital stay were significantly longer in the OG group. Complication rates were similar among the groups. A sub-analysis on minimally invasive (RG = 19 vs. LG = 20) wedge resections and hand/robot-sewn suture showed that operative time was longer in the RGs (p = 0.007). No conversions were recorded in the RG group versus three in the LG group (p = 0.231). Safety-related factors were similar. CONCLUSIONS: Gastric GIST can be safely treated with a minimally invasive approach which is also associated with improved postoperative outcomes.
PURPOSE: To present the outcomes of gastric gastrointestinal stromal tumour (GIST) resection from five Italian centres, focussing the analysis on the comparison among open (OG), laparoscopic (LG) and robotic (RG) approaches. METHODS: All consecutive gastric wedge resections for GIST between 2009 and 2019 were included. RESULTS: In total 101 (OG = 14, LG = 63 and RG = 24) were included. No differences were seen in the preoperative characteristics among the groups. Robotic procedures were longer (RG 180 min vs. LG 100 vs. OG 110; p < 0.0001). Time-to-first flatus and length of hospital stay were significantly longer in the OG group. Complication rates were similar among the groups. A sub-analysis on minimally invasive (RG = 19 vs. LG = 20) wedge resections and hand/robot-sewn suture showed that operative time was longer in the RGs (p = 0.007). No conversions were recorded in the RG group versus three in the LG group (p = 0.231). Safety-related factors were similar. CONCLUSIONS:Gastric GIST can be safely treated with a minimally invasive approach which is also associated with improved postoperative outcomes.