Literature DB >> 33130143

Ultrasonic Imaging Combined with Hysteroscopy in Diagnosis of Endometrial Polyps Based on Multioperator Algorithm and Analysis of Nerve Growth Factor Receptor Transmembrane Protein Expression.

Yun Gui1, Lin Wang2, Ting Gao1, Hui Hong1, Weidong Zhao3.   

Abstract

The paper aims to understand the expression of nerve growth factor receptor (TrkA) in the ectopic and entopic endometrium of patients with adenomyosis and dysmenorrhea and, at the same time, explore and analyze the combination of hysteroscopy and ultrasound imaging based on multioperator algorithms. The clinical treatment value of color Doppler ultrasound in the diagnosis and treatment of endometrial polyps. The immunohistochemical avidin-peroxidase staining method (SP method) was used to detect 20 cases of ectopic endometrium and entopic endometrium in patients with dysmenorrhea of adenomyosis (study group) and 22 cases of uterine fibroids in the control group. The expression of nerve growth factor receptor in the endometrium of patients with dysmenorrhea and comparative analysis. At the same time, all patients were examined by transvaginal color Doppler ultrasound and hysteroscopy. The scores of endometrial polyps, diagnostic efficiency of the methods, and receiver operating characteristic curve analysis of various diagnostic methods were observed and recorded in the 2 groups. There was no significant difference in the expression of TrkA in the ectopic endometrium and the entopic endometrium in the study group (P > 0.05), but the expression intensity of TrkA in the 2 groups was significantly higher than that in the control group (P = 0.05). In the diagnosis of endometrial polyps, the area of receiver operating characteristic curve in the parallel combined diagnosis of ultrasound and hysteroscopy is significantly larger than that under the combined diagnosis of series. TrkA is widely expressed in the ectopic and entopic endometrium of patients with adenomyosis and dysmenorrhea and may play an important role in the onset of adenomyosis and dysmenorrhea. Hysteroscopy combined with color Doppler ultrasound can effectively improve the diagnostic accuracy of patients with endometrial polyps.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Keywords:  Endometrial polyps; Hysteroscopy; Multioperator algorithm; Nerve growth factor receptor; Transmembrane protein expression; Ultrasound imaging

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Year:  2020        PMID: 33130143     DOI: 10.1016/j.wneu.2020.10.137

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  1 in total

1.  Comparison of Diagnostic Efficacy among Transvaginal Sonography, Transabdominal Sonography, and 3.0 T Magnetic Resonance Imaging in Early Cesarean Scar Pregnancy.

Authors:  Ke Wang; Fangbin Jing
Journal:  J Healthc Eng       Date:  2022-01-25       Impact factor: 2.682

  1 in total

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