Literature DB >> 33128870

A Blueprint for Characterizing Senescence.

Ananda L Roy1, Felipe Sierra2, Kevin Howcroft3, Dinah S Singer3, Norman Sharpless3, Richard J Hodes2, Elizabeth L Wilder4, James M Anderson5.   

Abstract

Given the heterogeneity of senescent cells, our knowledge of both the drivers and consequences of cellular senescence in tissues and organs remains limited, as is our understanding of how this process could be harnessed for human health. Here we identified five broad areas that would help propel the field forward. Published by Elsevier Inc.

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Year:  2020        PMID： 33128870     DOI： 10.1016/j.cell.2020.10.032

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  17 in total

1.  An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo.

Authors:  Binsheng Wang; Lichao Wang; Nathan S Gasek; Yueying Zhou; Taewan Kim; Chun Guo; Evan R Jellison; Laura Haynes; Sumit Yadav; Tamar Tchkonia; George A Kuchel; James L Kirkland; Ming Xu
Journal:  Nat Aging       Date:  2021-10-07

Review 2.  Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop.

Authors:  Tina E Brinkley; Jamie N Justice; Shubhashrita Basu; Scott R Bauer; Kah Poh Loh; Peter Mukli; Ted Kheng Siang Ng; Indira C Turney; Luigi Ferrucci; Steven R Cummings; Stephen B Kritchevsky
Journal:  Geroscience       Date:  2022-10-15       Impact factor: 7.581

3.  A BDNF-TrkB autocrine loop enhances senescent cell viability.

Authors:  Carlos Anerillas; Allison B Herman; Rachel Munk; Amanda Garrido; Kwan-Wood Gabriel Lam; Matthew J Payea; Martina Rossi; Dimitrios Tsitsipatis; Jennifer L Martindale; Yulan Piao; Krystyna Mazan-Mamczarz; Jinshui Fan; Chang-Yi Cui; Supriyo De; Kotb Abdelmohsen; Rafael de Cabo; Myriam Gorospe
Journal:  Nat Commun       Date:  2022-10-20       Impact factor: 17.694

Review 4.  A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.

Authors:  Mitzi M Gonzales; Sudarshan Krishnamurthy; Valentina Garbarino; Ali S Daeihagh; Gregory J Gillispie; Gagan Deep; Suzanne Craft; Miranda E Orr
Journal:  Mech Ageing Dev       Date:  2021-10-21       Impact factor: 5.498

Review 5.  Evidence of the Cellular Senescence Stress Response in Mitotically Active Brain Cells-Implications for Cancer and Neurodegeneration.

Authors:  Gregory J Gillispie; Eric Sah; Sudarshan Krishnamurthy; Mohamed Y Ahmidouch; Bin Zhang; Miranda E Orr
Journal:  Life (Basel)       Date:  2021-02-17

Review 6.  The Cellular Senescence Stress Response in Post-Mitotic Brain Cells: Cell Survival at the Expense of Tissue Degeneration.

Authors:  Eric Sah; Sudarshan Krishnamurthy; Mohamed Y Ahmidouch; Gregory J Gillispie; Carol Milligan; Miranda E Orr
Journal:  Life (Basel)       Date:  2021-03-11

Review 7.  Transcriptomic Analysis of Cellular Senescence: One Step Closer to Senescence Atlas.

Authors:  Sohee Kim; Chuna Kim
Journal:  Mol Cells       Date:  2021-03-31       Impact factor: 5.034

8.  Biochemical and Cellular Characterization of New Radio-Resistant Cell Lines Reveals a Role of Natural Flavonoids to Bypass Senescence.

Authors:  Maria Russo; Carmela Spagnuolo; Stefania Moccia; Idolo Tedesco; Fabio Lauria; Gian Luigi Russo
Journal:  Int J Mol Sci       Date:  2021-12-28       Impact factor: 5.923

Review 9.  The Olfactory System as Marker of Neurodegeneration in Aging, Neurological and Neuropsychiatric Disorders.

Authors:  Naina Bhatia-Dey; Thomas Heinbockel
Journal:  Int J Environ Res Public Health       Date:  2021-06-29       Impact factor: 3.390

Review 10.  Cellular Senescence in Cardiovascular Diseases: A Systematic Review.

Authors:  Can Hu; Xin Zhang; Teng Teng; Zhen-Guo Ma; Qi-Zhu Tang
Journal:  Aging Dis       Date:  2022-02-01       Impact factor: 6.745
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