| Literature DB >> 33125888 |
Rigel J Kishton1, Rachel C Lynn2, Nicholas P Restifo3.
Abstract
Targeting cancer neoantigens generated by tumor-exclusive somatic mutations is an attractive yet challenging strategy for the robust and specific elimination of tumor cells by cellular immunotherapy. In this issue of Cell, Wells et al. describe a consortium-based approach to optimize bioinformatics pipelines to sensitively and accurately predict immunogenic neoantigens from next-generation sequencing data.Entities:
Year: 2020 PMID: 33125888 DOI: 10.1016/j.cell.2020.10.011
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582