| Literature DB >> 33125677 |
Piotr Podwalski1, Krzysztof Szczygieł2, Ernest Tyburski3, Leszek Sagan4, Błażej Misiak5, Jerzy Samochowiec2.
Abstract
Diffusion tensor imaging (DTI) is an imaging technique that uses magnetic resonance. It measures the diffusion of water molecules in tissues, which can occur either without restriction (i.e., in an isotropic manner) or limited by some obstacles, such as cell membranes (i.e., in an anisotropic manner). Diffusion is most often measured in terms of, inter alia, fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (AD). DTI allows us to reconstruct, visualize, and evaluate certain qualities of white matter. To date, many studies have sought to associate various changes in the distribution of diffusion within the brain with mental diseases and disorders. A better understanding of white matter integrity disorders can help us recognize the causes of diseases, as well as help create objective methods of psychiatric diagnosis, identify biomarkers of mental illness, and improve pharmacotherapy. The aim of this work is to present the characteristics of DTI as well as current research on its use in schizophrenia, affective disorders, and other mental disorders.Entities:
Keywords: Affective disorders; DTI; Diffusion tensor imaging; Fractional anisotropy; Personality disorders; Schizophrenia
Year: 2020 PMID: 33125677 PMCID: PMC7862529 DOI: 10.1007/s43440-020-00177-0
Source DB: PubMed Journal: Pharmacol Rep ISSN: 1734-1140 Impact factor: 3.024