Literature DB >> 33120024

Developing Collaborative Platforms to Advance Neurotechnology and Its Translation.

David A Borton1, Heather E Dawes2, Gregory A Worrell3, Philip A Starr2, Timothy J Denison4.   

Abstract

Neurotechnological devices are failing to deliver on their therapeutic promise because of the time it takes to translate them from bench to clinic. In this Perspective, we reflect on lessons learned from medical device successes and failures and consider how such lessons might shape a strategic vision for translating neurotechnologies in the future. We articulate how the intentional design and deployment of "scientific platforms," from the technology stack of hardware and software through the supporting ecosystem, could catalyze a new wave of innovation, discovery, and therapy. We also identify specific actions that could promote future neurotechnology roadmaps and industrial-academic-government collaborative activities. We believe that community-supported neurotechnology platforms will prove to be transformational in accelerating ideas from bench to bedside, maximizing scientific discovery and improving patient care.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 33120024      PMCID: PMC7610607          DOI: 10.1016/j.neuron.2020.10.001

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  51 in total

1.  A Chronically Implantable Neural Coprocessor for Investigating the Treatment of Neurological Disorders.

Authors:  Scott Stanslaski; Jeffrey Herron; Tom Chouinard; Duane Bourget; Ben Isaacson; Vaclav Kremen; Enrico Opri; William Drew; Benjamin H Brinkmann; Aysegul Gunduz; Tom Adamski; Gregory A Worrell; Timothy Denison
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2018-11-07       Impact factor: 3.833

2.  Listening to Brain Microcircuits for Interfacing With External World-Progress in Wireless Implantable Microelectronic Neuroengineering Devices: Experimental systems are described for electrical recording in the brain using multiple microelectrodes and short range implantable or wearable broadcasting units.

Authors:  Arto V Nurmikko; John P Donoghue; Leigh R Hochberg; William R Patterson; Yoon-Kyu Song; Christopher W Bull; David A Borton; Farah Laiwalla; Sunmee Park; Yin Ming; Juan Aceros
Journal:  Proc IEEE Inst Electr Electron Eng       Date:  2010       Impact factor: 10.961

Review 3.  The cost of brain diseases: a burden or a challenge?

Authors:  Monica DiLuca; Jes Olesen
Journal:  Neuron       Date:  2014-06-18       Impact factor: 17.173

4.  Drug discovery: a jump-start for electroceuticals.

Authors:  Kristoffer Famm; Brian Litt; Kevin J Tracey; Edward S Boyden; Moncef Slaoui
Journal:  Nature       Date:  2013-04-11       Impact factor: 49.962

5.  Adaptive deep brain stimulation for Parkinson's disease using motor cortex sensing.

Authors:  Nicole C Swann; Coralie de Hemptinne; Margaret C Thompson; Svjetlana Miocinovic; Andrew M Miller; Ro'ee Gilron; Jill L Ostrem; Howard J Chizeck; Philip A Starr
Journal:  J Neural Eng       Date:  2018-05-09       Impact factor: 5.379

6.  Integrating Brain Implants With Local and Distributed Computing Devices: A Next Generation Epilepsy Management System.

Authors:  Vaclav Kremen; Benjamin H Brinkmann; Inyong Kim; Hari Guragain; Mona Nasseri; Abigail L Magee; Tal Pal Attia; Petr Nejedly; Vladimir Sladky; Nathanial Nelson; Su-Youne Chang; Jeffrey A Herron; Tom Adamski; Steven Baldassano; Jan Cimbalnik; Vince Vasoli; Elizabeth Fehrmann; Tom Chouinard; Edward E Patterson; Brian Litt; Matt Stead; Jamie Van Gompel; Beverly K Sturges; Hang Joon Jo; Chelsea M Crowe; Timothy Denison; Gregory A Worrell
Journal:  IEEE J Transl Eng Health Med       Date:  2018-09-26

7.  A brain-spine interface alleviating gait deficits after spinal cord injury in primates.

Authors:  Marco Capogrosso; Tomislav Milekovic; David Borton; Fabien Wagner; Eduardo Martin Moraud; Jean-Baptiste Mignardot; Nicolas Buse; Jerome Gandar; Quentin Barraud; David Xing; Elodie Rey; Simone Duis; Yang Jianzhong; Wai Kin D Ko; Qin Li; Peter Detemple; Tim Denison; Silvestro Micera; Erwan Bezard; Jocelyne Bloch; Grégoire Courtine
Journal:  Nature       Date:  2016-11-10       Impact factor: 49.962

8.  A connectomic approach for subcallosal cingulate deep brain stimulation surgery: prospective targeting in treatment-resistant depression.

Authors:  P Riva-Posse; K S Choi; P E Holtzheimer; A L Crowell; S J Garlow; J K Rajendra; C C McIntyre; R E Gross; H S Mayberg
Journal:  Mol Psychiatry       Date:  2017-04-11       Impact factor: 15.992

9.  Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration.

Authors:  A Bolu Ajiboye; Francis R Willett; Daniel R Young; William D Memberg; Brian A Murphy; Jonathan P Miller; Benjamin L Walter; Jennifer A Sweet; Harry A Hoyen; Michael W Keith; P Hunter Peckham; John D Simeral; John P Donoghue; Leigh R Hochberg; Robert F Kirsch
Journal:  Lancet       Date:  2017-03-28       Impact factor: 79.321

10.  Stability of a chronic implanted brain-computer interface in late-stage amyotrophic lateral sclerosis.

Authors:  Elmar G M Pels; Erik J Aarnoutse; Sacha Leinders; Zac V Freudenburg; Mariana P Branco; Benny H van der Vijgh; Tom J Snijders; Timothy Denison; Mariska J Vansteensel; Nick F Ramsey
Journal:  Clin Neurophysiol       Date:  2019-07-27       Impact factor: 3.708

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  10 in total

1.  Distributed brain co-processor for tracking spikes, seizures and behaviour during electrical brain stimulation.

Authors:  Vladimir Sladky; Petr Nejedly; Filip Mivalt; Benjamin H Brinkmann; Inyong Kim; Erik K St Louis; Nicholas M Gregg; Brian N Lundstrom; Chelsea M Crowe; Tal Pal Attia; Daniel Crepeau; Irena Balzekas; Victoria S Marks; Lydia P Wheeler; Jan Cimbalnik; Mark Cook; Radek Janca; Beverly K Sturges; Kent Leyde; Kai J Miller; Jamie J Van Gompel; Timothy Denison; Gregory A Worrell; Vaclav Kremen
Journal:  Brain Commun       Date:  2022-05-06

2.  DyNeuMo Mk-1: Design and pilot validation of an investigational motion-adaptive neurostimulator with integrated chronotherapy.

Authors:  Mayela Zamora; Robert Toth; Francesca Morgante; Jon Ottaway; Tom Gillbe; Sean Martin; Guy Lamb; Tara Noone; Moaad Benjaber; Zachary Nairac; Devang Sehgal; Timothy G Constandinou; Jeffrey Herron; Tipu Z Aziz; Ivor Gillbe; Alexander L Green; Erlick A C Pereira; Timothy Denison
Journal:  Exp Neurol       Date:  2022-01-10       Impact factor: 5.620

3.  Design and Testing of Stimulation and Myoelectric Recording Modules in an Implanted Distributed Neuroprosthetic System.

Authors:  Nathaniel Makowski; Alexandru Campean; Joris Lambrecht; James Buckett; James Coburn; Ronald Hart; Michael Miller; Fred Montague; Timothy Crish; Michael Fu; Kevin Kilgore; P Hunter Peckham; Brian Smith
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2021-05-25       Impact factor: 5.234

4.  A spiking neural network (SNN) for detecting high frequency oscillations (HFOs) in the intraoperative ECoG.

Authors:  Karla Burelo; Mohammadali Sharifshazileh; Niklaus Krayenbühl; Georgia Ramantani; Giacomo Indiveri; Johannes Sarnthein
Journal:  Sci Rep       Date:  2021-03-24       Impact factor: 4.379

Review 5.  Neuromodulation in 2035: The Neurology Future Forecasting Series.

Authors:  Tim Denison; Martha J Morrell
Journal:  Neurology       Date:  2022-01-11       Impact factor: 11.800

6.  The Role of Large-Scale Data Infrastructure in Developing Next-Generation Deep Brain Stimulation Therapies.

Authors:  Witney Chen; Lowry Kirkby; Miro Kotzev; Patrick Song; Ro'ee Gilron; Brian Pepin
Journal:  Front Hum Neurosci       Date:  2021-09-06       Impact factor: 3.169

7.  Physiologically informed neuromodulation.

Authors:  Karen Wendt; Timothy Denison; Gaynor Foster; Lothar Krinke; Alix Thomson; Saydra Wilson; Alik S Widge
Journal:  J Neurol Sci       Date:  2021-12-28       Impact factor: 3.181

Review 8.  Translational research in health technologies: A scoping review.

Authors:  Nadja N V Mayrink; Luís Alcoforado; Arthur Chioro; Felipe Fernandes; Thaisa S Lima; Erika B Camargo; Ricardo A M Valentim
Journal:  Front Digit Health       Date:  2022-08-03

9.  Stimulating Solutions for Intractable Epilepsy.

Authors:  Timothy Denison; Mohamad Koubeissi; Esther Krook-Magnuson; David Mogul; Gregory Worrell; Catherine Schevon
Journal:  Epilepsy Curr       Date:  2021-04-30       Impact factor: 7.500

10.  Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.

Authors:  Kristin K Sellers; Ro'ee Gilron; Juan Anso; Kenneth H Louie; Prasad R Shirvalkar; Edward F Chang; Simon J Little; Philip A Starr
Journal:  Front Hum Neurosci       Date:  2021-07-12       Impact factor: 3.169

  10 in total

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