Literature DB >> 3311865

The binding rate of sialic acid to serum alpha 1-acid glycoprotein in patients with chronic hepatic injury.

T Ozeki1, Y Okada, K Iwaki.   

Abstract

The level of serum orosomucoid, the amount of sialic acid binding to it, and the binding rate of sialic acid to orosomucoid in normal individuals and in patients with chronic hepatitis and liver cirrhosis were determined by affinity column chromatography, SDS electrophoresis and the method of Warren. Although no apparent changes in the level of serum orosomucoid or the amount of sialic acid binding to it in each group were seen, the binding rate of sialic acid to orosomucoid in chronic persistent hepatitis and chronic active hepatitis showed a remarkable increase, compared with normal individuals and patients with liver cirrhosis. Furthermore, the binding rate of sialic acid in liver cirrhosis was the lowest in each group.

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Year:  1987        PMID: 3311865     DOI: 10.1007/BF02773812

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN: 0435-1339


  13 in total

1.  Sunthesis of alphal-acid glycoprotein by the isolated perfused rat liver.

Authors:  E J SARCIONE
Journal:  Arch Biochem Biophys       Date:  1963-03       Impact factor: 4.013

2.  Plasma glycoproteins, mucoproteins, and mucopolysaccharides.

Authors:  A J BOLLET
Journal:  AMA Arch Intern Med       Date:  1959-07

3.  The effect of the sialyl residues on the thermodynamic and hydrodynamic properties of 1 -acid glycoprotein.

Authors:  K Hawahara; T Ikenaka; R B Nimberg; K Schmid
Journal:  Biochim Biophys Acta       Date:  1973-02-21

4.  Microtubule-depolymerizing agents inhibit asialo-orosomucoid delivery to lysosomes but not its endocytosis or degradation in isolated rat hepatocytes.

Authors:  J A Oka; P H Weigel
Journal:  Biochim Biophys Acta       Date:  1983-12-19

5.  Asialoglycoprotein receptors in hepatic regeneration.

Authors:  D J Howard; R J Stockert; A G Morell
Journal:  J Biol Chem       Date:  1982-03-25       Impact factor: 5.157

6.  Turnover of the surface proteins and the receptor for serum asialoglycoproteins in primary cultures of rat hepatocytes.

Authors:  R Warren; D Doyle
Journal:  J Biol Chem       Date:  1981-02-10       Impact factor: 5.157

7.  Acute and chronic hepatitis revisited. Review by an international group.

Authors: 
Journal:  Lancet       Date:  1977-10-29       Impact factor: 79.321

8.  Isolation and characterization of alpha 1-acid glycoprotein from chimpanzee plasma.

Authors:  Y T Li; S C Li
Journal:  J Biol Chem       Date:  1970-02-25       Impact factor: 5.157

9.  Structures of the oligosaccharide chains of two forms of alpha 1-acid glycoprotein purified from liver metastases of lung, colon, and breast tumors.

Authors:  E V Chandrasekaran; M Davila; D Nixon; J Mendicino
Journal:  Cancer Res       Date:  1984-04       Impact factor: 12.701

10.  Measurement of serum alpha 1-acid glycoprotein and alpha 1-antitrypsin desialylation in liver disease.

Authors:  N Serbource-Goguel; M Corbic; S Erlinger; G Durand; J Agneray; J Feger
Journal:  Hepatology       Date:  1983 May-Jun       Impact factor: 17.425

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