Literature DB >> 33118483

Use of cord blood platelet gel to enhance healing of deep surgical site dehiscences after peripheral bypass.

Pietro Volpe1, Giulia Pucci2, Giuseppe Stilo1, Antonino Alberti1, Giovanni Foti2, Rosangela Surace2, Mafalda Massara1.   

Abstract

Surgical site dehiscence after lower limb revascularization through bypass represents a serious postoperative complication, especially in diabetic and obese patients, with subsequent risk of early graft failure, infection, sepsis, hemorrhage, major amputation and sometimes death. To prevent bypass exposure and subsequent complications, physicians recur to reoperation, antibiotic therapy, advanced dressing and vacuum-assisted closure therapy. To improve the process of wound healing, cord blood platelet gel can be used to fill deep and large wounds. Growth factors released from platelets in the cord blood platelet gel stimulate the process of healing and allow patients to be followed up in Outpatient Surgery, thus reducing hospital stay and costs, while providing excellent results.

Entities:  

Keywords:  cord blood platelet gel; growth factors; obesity; peripheral bypass; surgical site dehiscence; wound healing

Year:  2020        PMID: 33118483     DOI: 10.2217/rme-2020-0034

Source DB:  PubMed          Journal:  Regen Med        ISSN: 1746-0751            Impact factor:   3.806


  2 in total

1.  Selection Criteria of Cord Blood Units for Platelet Gel Production: Proposed Directions from Hellenic Cord Blood Bank. Comment on Mallis et al. Short Term Results of Fibrin Gel Obtained from Cord Blood Units: A Preliminary in Vitro Study. Bioengineering 2019, 6, 66.

Authors:  Panagiotis Mallis; Efstathios Michalopoulos; Effrosyni Panagouli; Zetta Dimou; Eirini Faidra Sarri; Eleni Georgiou; Vasiliki Gkioka; Catherine Stavropoulos-Giokas
Journal:  Bioengineering (Basel)       Date:  2021-04-27

2.  Recycling Apparent Waste Into Biologicals: The Case of Umbilical Cord Blood in Italy and Spain.

Authors:  Paolo Rebulla; Sergio Querol; Simonetta Pupella; Daniele Prati; Joaquin Delgadillo; Vincenzo De Angelis
Journal:  Front Cell Dev Biol       Date:  2022-01-04
  2 in total

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