Literature DB >> 3311708

Opiate withdrawal and electro-stimulation. Double blind experiments.

F Ellison1, W Ellison, J P Daulouede, J F Daubech, B Pautrizel, M Bourgeois, J Tignol.   

Abstract

A rapid detoxification technique for heroin addicts is described. The technique uses an impulsional electric current developed by Limoge. The treatment is nonaggressive, very well tolerated by the addicts and leads to a good psychotherapeutic relationship with the medical staff. A successful physical detoxification is achieved in more than 80% of the cases (this figure is based on 400 patients treated by the method). The technique was subjected to two double-blind experiments. The first experiment tested the real efficacity of the electrical stimulation. The difference between the group of subjects stimulated and the unstimulated control group had a "p-value" which was significant at the 0,5% level. This leads us to believe that the electrical stimulation has a real positive effect. The second experiment reconfirmed the efficacity of the stimulation and showed that 24 hour continuous stimulation was not sufficient to produce a lasting effect. After about 50 hours stimulation a Naloxone test produced little or no reaction in the patients.

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Year:  1987        PMID: 3311708

Source DB:  PubMed          Journal:  Encephale        ISSN: 0013-7006            Impact factor:   1.291


  2 in total

1.  Transcutaneous Auricular Neurostimulation (tAN): A Novel Adjuvant Treatment in Neonatal Opioid Withdrawal Syndrome.

Authors:  Dorothea D Jenkins; Navid Khodaparast; Georgia H O'Leary; Stephanie N Washburn; Alejandro Covalin; Bashar W Badran
Journal:  Front Hum Neurosci       Date:  2021-03-08       Impact factor: 3.169

2.  Delivering transcutaneous auricular neurostimulation (tAN) to improve symptoms associated with opioid withdrawal: results from a prospective clinical trial.

Authors:  Carlos F Tirado; Stephanie N Washburn; Alejandro Covalin; Caroline Hedenberg; Heather Vanderpool; Caroline Benner; Daniel P Powell; Melanie A McWade; Navid Khodaparast
Journal:  Bioelectron Med       Date:  2022-08-18
  2 in total

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