Literature DB >> 3311380

Immunocytochemical localization of a novel pituitary polypeptide "7B2" in the gastro-intestinal tract of the rat.

J P Falgueyret1, M Marcinkiewicz, S Benjannet, M Cantin, N G Seidah, M Chrétien.   

Abstract

Immunoreactivity to the polypeptide designated "7B2" recently isolated from human and porcine pituitary glands, appears to be consistently confined to neuroendocrine and endocrine cells in various tissues. In rat gut, immunoreactive 7B2 was found in endocrine-paracrine cells. Highly labeled cells were found in the antrum of the stomach and, cells with lower concentrations, in the fundus, duodenum, jejunum and ileum. Except for a few cells which were simultaneously positive for 5-hydroxytryptamine, and a few others showing Grimelius's reaction, "7B2" cells do not exhibit argentaffin and/or argyrophil character. The 7B2 polypeptide seems to be distributed amongst several different types of endocrine cells in the gut.

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Year:  1987        PMID： 3311380     DOI： 10.1007/BF00217343

Source DB:  PubMed          Journal:  Cell Tissue Res        ISSN： 0302-766X            Impact factor:   5.249


  8 in total

1.  A silver nitrate stain for alpha-2 cells in human pancreatic islets.

Authors:  L Grimelius
Journal:  Acta Soc Med Ups       Date:  1968

2.  CNS distribution of a novel pituitary protein '7B2': localization in secretory and synaptic vesicles.

Authors:  M Marcinkiewicz; S Benjannet; M Cantin; N G Seidah; M Chrétien
Journal:  Brain Res       Date:  1986-08-20       Impact factor: 3.252

3.  Isolation and NH2-terminal sequence of a highly conserved human and porcine pituitary protein belonging to a new superfamily. Immunocytochemical localization in pars distalis and pars nervosa of the pituitary and in the supraoptic nucleus of the hypothalamus.

Authors:  N G Seidah; K L Hsi; G De Serres; J Rochemont; J Hamelin; T Antakly; M Cantin; M Chrétien
Journal:  Arch Biochem Biophys       Date:  1983-09       Impact factor: 4.013

4.  Isolation and NH2-terminal sequence of a novel porcine anterior pituitary polypeptide. Homology to proinsulin, secretin and Rous sarcoma virus transforming protein TVFV60.

Authors:  K L Hsi; N G Seidah; G De Serres; M Chrétien
Journal:  FEBS Lett       Date:  1982-10-18       Impact factor: 4.124

5.  Immunocytochemical localization of a novel pituitary protein (7B2) within the rat brain and hypophysis.

Authors:  M Marcinkiewicz; S Benjannet; N G Seidah; M Cantin; M Chrétien
Journal:  J Histochem Cytochem       Date:  1985-12       Impact factor: 2.479

6.  Ontogeny of a novel pituitary protein (7B2) in the human fetal intestine.

Authors:  H Suzuki; N D Christofides; T E Adrian; M Chretien; N G Seidah; J M Polak; S R Bloom
Journal:  Regul Pept       Date:  1985-11-28

7.  Tissue distribution and molecular forms of a novel pituitary protein in the rat.

Authors:  H Iguchi; J S Chan; N G Seidah; M Chrétien
Journal:  Neuroendocrinology       Date:  1984-11       Impact factor: 4.914

8.  An unlabeled antibody method using glucose oxidase-antiglucose oxidase complexes (GAG): a sensitive alternative to immunoperoxidase for the detection of tissue antigens.

Authors:  C A Clark; E C Downs; F J Primus
Journal:  J Histochem Cytochem       Date:  1982-01       Impact factor: 2.479
  8 in total
  3 in total

1.  Carcinoid granule extract contains antigenic determinants common to peptide hormone-producing cells and endocrine tumours.

Authors:  L Larsson; J Alumets; R Håkanson; M Simonsson; F Sundler
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1990

Review 2.  Neuroendocrine secretory protein 7B2: structure, expression and functions.

Authors:  M Mbikay; N G Seidah; M Chrétien
Journal:  Biochem J       Date:  2001-07-15       Impact factor: 3.857

3.  Regulation by gastric acid of the processing of progastrin-derived peptides in rat antral mucosa.

Authors:  J A Macro; G W Bate; A Varro; C Vaillant; N G Seidah; R Dimaline; G J Dockray
Journal:  J Physiol       Date:  1997-07-15       Impact factor: 5.182
  3 in total

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