Laura Cano-García1,2, Natalia Mena-Vázquez1,2, Sara Manrique Arija1,2, María Dolores Hernández-Sánchez3, Rocío Segura-Ruiz4, Carmen Domínguez-Quesada5, Antonio Fernández-Nebro1,2,6. 1. Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain. 2. UGC de Reumatología, Hospital Regional Universitario de Málaga, Málaga, Spain. 3. UGC de Reumatología, Complejo Hospitalario de Jaén, Jaén, Spain. 4. UGC de Reumatología, Hospital Reina Sofía, Córdoba, Spain. 5. UGC Reumatología, Hospital Universitario Virgen Macarena, Sevilla, Spain. 6. Departamento de Medicina, Universidad de Málaga, Málaga, Spain.
Abstract
BACKGROUND: Studies in axial spondyloarthritis (AxSp) have shown that intensity of pain, anxiety, depression and inflammatory activity are associated with poor sleep quality. AIM: To describe mood and sleep disorders and positive psychological factors in patients with AxSp and psoriatic arthritis (PsA) and to evaluate the psychological factors that are potentially involved in sleep disorders. DESIGN: Multicenter cross-sectional observational study based on a series of patients with AxSp and PsA. PARTICIPANTS: Participants were selected consecutively from patients aged ≥18 years with AxSp or PsA followed at the rheumatology department of 4 Spanish hospitals. INCLUSION CRITERIA: age ≥18 years, AxSp (ASAS criteria) or PsA (CASPAR criteria), ability to understand the study and prepared to complete the questionnaires. METHODS: Main outcomes: Oviedo Sleep Quality questionnaire result. SECONDARY OUTCOMES: psychological status evaluated using the Hospital Anxiety and Depression Scale (HADS) questionnaire, health-related quality of life evaluated using SF-36, perception of pain evaluated using the short questionnaire for assessment of pain (BDU) and fatigue evaluated using the Fatigue Scale (FACIT) questionnaire. We performed a descriptive multivariate linear regression analysis to study factors that were independently associated with sleep disorders. The STROBE guidelines were adopted. RESULTS: We included 301 patients (152 [50.5%] with AxSp and 149 [49.5%] with PsA). The multivariate linear regression analysis for the whole sample showed that insomnia was inversely associated with emotional recovery and biologic disease-modifying antirheumatic drugs and directly associated with depression in both groups. The analysis by disease (AxSp and PsA) showed that insomnia was independently associated with depression and emotional recovery. CONCLUSIONS: Insomnia may be associated with other mood disorders, quality of life and inflammatory activity in the patients studied here. RELEVANCE TO CLINICAL PRACTICE: A nurse intervention can be carried out to prevent sleep disorders knowing the consequences and triggers of the problem.
BACKGROUND: Studies in axial spondyloarthritis (AxSp) have shown that intensity of pain, anxiety, depression and inflammatory activity are associated with poor sleep quality. AIM: To describe mood and sleep disorders and positive psychological factors in patients with AxSp and psoriatic arthritis (PsA) and to evaluate the psychological factors that are potentially involved in sleep disorders. DESIGN: Multicenter cross-sectional observational study based on a series of patients with AxSp and PsA. PARTICIPANTS: Participants were selected consecutively from patients aged ≥18 years with AxSp or PsA followed at the rheumatology department of 4 Spanish hospitals. INCLUSION CRITERIA: age ≥18 years, AxSp (ASAS criteria) or PsA (CASPAR criteria), ability to understand the study and prepared to complete the questionnaires. METHODS: Main outcomes: Oviedo Sleep Quality questionnaire result. SECONDARY OUTCOMES: psychological status evaluated using the Hospital Anxiety and Depression Scale (HADS) questionnaire, health-related quality of life evaluated using SF-36, perception of pain evaluated using the short questionnaire for assessment of pain (BDU) and fatigue evaluated using the Fatigue Scale (FACIT) questionnaire. We performed a descriptive multivariate linear regression analysis to study factors that were independently associated with sleep disorders. The STROBE guidelines were adopted. RESULTS: We included 301 patients (152 [50.5%] with AxSp and 149 [49.5%] with PsA). The multivariate linear regression analysis for the whole sample showed that insomnia was inversely associated with emotional recovery and biologic disease-modifying antirheumatic drugs and directly associated with depression in both groups. The analysis by disease (AxSp and PsA) showed that insomnia was independently associated with depression and emotional recovery. CONCLUSIONS:Insomnia may be associated with other mood disorders, quality of life and inflammatory activity in the patients studied here. RELEVANCE TO CLINICAL PRACTICE: A nurse intervention can be carried out to prevent sleep disorders knowing the consequences and triggers of the problem.
Authors: Natalia Mena-Vázquez; Fernando Ortiz-Márquez; Pablo Cabezudo-García; Claudia Padilla-Leiva; Gisela Diaz-Cordovés Rego; Luis Muñoz-Becerra; Teresa Ramírez-García; Jose Manuel Lisbona-Montañez; Sara Manrique-Arija; Arkaitz Mucientes; Esmeralda Núñez-Cuadros; Rocío Galindo Zavala; Pedro Jesús Serrano-Castro; Antonio Fernández-Nebro Journal: Biomedicines Date: 2022-07-18
Authors: Laura Cano-García; Natalia Mena-Vázquez; Sara Manrique-Arija; Rocío Redondo-Rodriguez; Carmen María Romero-Barco; Antonio Fernández-Nebro Journal: Diagnostics (Basel) Date: 2021-12-02