Literature DB >> 33111642

Noninvasive vagal nerve stimulation for gastroenterology pain disorders.

Andres Gottfried-Blackmore1, Aida Habtezion1, Linda Nguyen1.   

Abstract

Abdominal pain continues to be a major challenge and unmet need in clinical practice. Normalization of bidirectional gut-brain signaling has generated much interest as a therapeutic approach to treat chronic abdominal pain. Vagal nerve stimulation (VNS) is emerging as a potential non-pharmacologic strategy for the treatment of abdominal pain. In this review paper, we will summarize the etiologies of chronic pain in gastrointestinal disorders and discuss the rational for VNS as a therapeutic approach to chronic abdominal pain, with particular emphasis in the gammaCore stimulator which allows for noninvasive VNS.

Entities:  

Keywords:  central sensitization; gammaCore®; vagal nerve stimulation; visceral hypersensitivity

Mesh:

Year:  2020        PMID: 33111642      PMCID: PMC7787175          DOI: 10.2217/pmt-2020-0067

Source DB:  PubMed          Journal:  Pain Manag        ISSN: 1758-1869


  52 in total

Review 1.  Abdominal vagal afferent neurones: an important target for the treatment of gastrointestinal dysfunction.

Authors:  Paul L R Andrews; Gareth J Sanger
Journal:  Curr Opin Pharmacol       Date:  2002-12       Impact factor: 5.547

2.  Anti-inflammatory effect of vagus nerve stimulation in a rat model of inflammatory bowel disease.

Authors:  J Meregnani; D Clarençon; M Vivier; A Peinnequin; C Mouret; V Sinniger; C Picq; A Job; F Canini; M Jacquier-Sarlin; Bruno Bonaz
Journal:  Auton Neurosci       Date:  2010-11-11       Impact factor: 3.145

3.  Reflexes in Immunity.

Authors:  Kevin J Tracey
Journal:  Cell       Date:  2016-01-28       Impact factor: 41.582

4.  The Abdominal Distribution of the Vagus.

Authors:  E D McCrea
Journal:  J Anat       Date:  1924-10       Impact factor: 2.610

5.  Severe gastroparesis: medical therapy or gastric electrical stimulation.

Authors:  Savio C Reddymasu; Irene Sarosiek; Richard W McCallum
Journal:  Clin Gastroenterol Hepatol       Date:  2009-09-16       Impact factor: 11.382

6.  Modulation of vagal tone enhances gastroduodenal motility and reduces somatic pain sensitivity.

Authors:  J B Frøkjaer; S Bergmann; C Brock; A Madzak; A D Farmer; J Ellrich; A M Drewes
Journal:  Neurogastroenterol Motil       Date:  2016-01-04       Impact factor: 3.598

Review 7.  Neural plasticity in the gastrointestinal tract: chronic inflammation, neurotrophic signals, and hypersensitivity.

Authors:  Ihsan Ekin Demir; Karl-Herbert Schäfer; Elke Tieftrunk; Helmut Friess; Güralp O Ceyhan
Journal:  Acta Neuropathol       Date:  2013-02-17       Impact factor: 17.088

8.  Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.

Authors:  Frieda A Koopman; Sangeeta S Chavan; Sanda Miljko; Simeon Grazio; Sekib Sokolovic; P Richard Schuurman; Ashesh D Mehta; Yaakov A Levine; Michael Faltys; Ralph Zitnik; Kevin J Tracey; Paul P Tak
Journal:  Proc Natl Acad Sci U S A       Date:  2016-07-05       Impact factor: 11.205

Review 9.  Vagus nerve stimulation in clinical practice.

Authors:  Adam D Farmer; Ahmed Albu-Soda; Qasim Aziz
Journal:  Br J Hosp Med (Lond)       Date:  2016-11-02       Impact factor: 0.825

10.  Gastric electrical stimulation with Enterra therapy improves symptoms of idiopathic gastroparesis.

Authors:  R W McCallum; I Sarosiek; H P Parkman; W Snape; F Brody; J Wo; T Nowak
Journal:  Neurogastroenterol Motil       Date:  2013-07-29       Impact factor: 3.598

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