| Literature DB >> 33111642 |
Andres Gottfried-Blackmore1, Aida Habtezion1, Linda Nguyen1.
Abstract
Abdominal pain continues to be a major challenge and unmet need in clinical practice. Normalization of bidirectional gut-brain signaling has generated much interest as a therapeutic approach to treat chronic abdominal pain. Vagal nerve stimulation (VNS) is emerging as a potential non-pharmacologic strategy for the treatment of abdominal pain. In this review paper, we will summarize the etiologies of chronic pain in gastrointestinal disorders and discuss the rational for VNS as a therapeutic approach to chronic abdominal pain, with particular emphasis in the gammaCore stimulator which allows for noninvasive VNS.Entities:
Keywords: central sensitization; gammaCore®; vagal nerve stimulation; visceral hypersensitivity
Mesh:
Year: 2020 PMID: 33111642 PMCID: PMC7787175 DOI: 10.2217/pmt-2020-0067
Source DB: PubMed Journal: Pain Manag ISSN: 1758-1869