Literature DB >> 33111593

Novel Neurotechnological Interventions for Pediatric Drug-Resistant Epilepsy: Physician Perspectives.

Patrick J McDonald1,2, Viorica Hrincu1, Mary B Connolly3, Mark J Harrison4,5, George M Ibrahim6, Robert P Naftel7, Winston Chiong8, Farhad Udwadia1, Judy Illes1.   

Abstract

This qualitative study investigated factors that guide physicians' choices for minimally invasive and neuromodulatory interventions as alternatives to conventional surgery or medical management for pediatric drug-resistant epilepsy. North American physicians were recruited to one of 4 focus groups at national conferences. Discussions were analyzed using qualitative content analysis. A pragmatic neuroethics framework was applied to interpret results. Discussions revealed 2 major thematic branches: (1) clinical decision making and (2) ethical considerations. Under clinical decision making, physicians emphasized scientific evidence and patient candidacy when assessing neurotechnologies for patients. Ongoing seizures without intervention was important for safety and neurodevelopment. Under ethical considerations, resource allocation, among other financial considerations for technology adoption, were considerable sources of pressure on decision making. Access to neurotechnology was a salient theme differentiating Canadian and American contexts. When assessing novel neurotechnological interventions for pediatric drug-resistant epilepsy, physicians balance clinical and ethical factors to guide decision making and best practice.

Entities:  

Keywords:  epilepsy; ethics; neurosurgery; pediatric; treatment

Mesh:

Year:  2020        PMID: 33111593      PMCID: PMC7855396          DOI: 10.1177/0883073820966935

Source DB:  PubMed          Journal:  J Child Neurol        ISSN: 0883-0738            Impact factor:   1.987


  25 in total

1.  The qualitative content analysis process.

Authors:  Satu Elo; Helvi Kyngäs
Journal:  J Adv Nurs       Date:  2008-04       Impact factor: 3.187

2.  Dissociations in the meaning of risk between health-care professionals and individuals with spinal cord injury.

Authors:  M Eijkholt; B K Kwon; J Illes
Journal:  Spinal Cord       Date:  2013-09-17       Impact factor: 2.772

3.  Stem cell clinical trials for spinal cord injury: readiness, reluctance, redefinition.

Authors:  J Illes; J C Reimer; B K Kwon
Journal:  Stem Cell Rev Rep       Date:  2011-11       Impact factor: 5.739

4.  Device representatives in hospitals: are commercial imperatives driving clinical decision-making?

Authors:  Quinn Grundy; Katrina Hutchison; Jane Johnson; Brette Blakely; Robyn Clay-Wlliams; Bernadette Richards; Wendy A Rogers
Journal:  J Med Ethics       Date:  2018-07-04       Impact factor: 2.903

5.  ELSI priorities for brain imaging.

Authors:  Judy Illes; Raymond De Vries; Mildred K Cho; Pam Schraedley-Desmond
Journal:  Am J Bioeth       Date:  2006 Mar-Apr       Impact factor: 11.229

6.  Early identification of refractory epilepsy.

Authors:  P Kwan; M J Brodie
Journal:  N Engl J Med       Date:  2000-02-03       Impact factor: 91.245

7.  Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies.

Authors:  Patrick Kwan; Alexis Arzimanoglou; Anne T Berg; Martin J Brodie; W Allen Hauser; Gary Mathern; Solomon L Moshé; Emilio Perucca; Samuel Wiebe; Jacqueline French
Journal:  Epilepsia       Date:  2009-11-03       Impact factor: 5.864

8.  Ethically Problematic Medical Device Representation.

Authors:  Judy Illes; Patrick J McDonald; Chloe Lau; Viorica M Hrincu; Mary B Connolly
Journal:  Am J Bioeth       Date:  2020-08       Impact factor: 11.229

9.  Putting children forward for epilepsy surgery: A qualitative study of UK parents' and health professionals' decision-making experiences.

Authors:  Gemma Heath; Shanara Abdin; Rahima Begum; Shauna Kearney
Journal:  Epilepsy Behav       Date:  2016-06-29       Impact factor: 2.937

10.  Embodiment and Estrangement: Results from a First-in-Human "Intelligent BCI" Trial.

Authors:  F Gilbert; M Cook; T O'Brien; J Illes
Journal:  Sci Eng Ethics       Date:  2017-11-11       Impact factor: 3.525

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  3 in total

1.  Understanding Attributes that Influence Physician and Caregiver Decisions About Neurotechnology for Pediatric Drug-Resistant Epilepsy: A Formative Qualitative Study to Support the Development of a Discrete Choice Experiment.

Authors:  Glory Apantaku; Magda Aguiar; K Julia Kaal; Patrick J McDonald; Mary B Connolly; Viorica Hrincu; Judy Illes; Mark Harrison
Journal:  Patient       Date:  2021-08-25       Impact factor: 3.883

2.  Ethical Considerations for Discrete Choice Experiments with Caregivers.

Authors:  Judy Illes; Ashley Lawson; Patrick J McDonald
Journal:  J Empir Res Hum Res Ethics       Date:  2022-07-18       Impact factor: 1.978

3.  Choice and Trade-offs: Parent Decision Making for Neurotechnologies for Pediatric Drug-Resistant Epilepsy.

Authors:  Viorica Hrincu; Patrick J McDonald; Mary B Connolly; Mark J Harrison; George M Ibrahim; Robert P Naftel; Winston Chiong; Armaghan Alam; Urs Ribary; Judy Illes
Journal:  J Child Neurol       Date:  2021-06-02       Impact factor: 1.987

  3 in total

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