Literature DB >> 33109335

Body Mass Index and Mortality in Blunt Trauma: The Right BMI can be Protective.

James Choi1, Abbas Smiley2, Rifat Latifi3, Shekhar Gogna4, Kartik Prabhakaran5, Jorge Con6, Patrice Anderson7, Anthony Policastro8, Malk Beydoun9, Peter Rhee10.   

Abstract

BACKGROUND: There are limited studies examining the role of BMI on mortality in the trauma population. The aim of this study was to analyze whether the "obesity paradox" exists in non-elderly patients with blunt trauma.
METHODS: A retrospective study was performed on the Trauma Quality Improvement Program (TQIP) database for 2016. All non-elderly patients aged 18-64, with blunt traumatic injuries were identified. A generalized additive model (GAM) was built to assess the association of mortality and BMI adjusted for age, gender, race, and injury severity score (ISS).
RESULTS: 28,475 patients (mean age = 42.5, SD = 14.3) were identified. 20,328 (71.4%) were male. Age (p < 0.0001), gender (p < 0.0001), and ISS (p < 0.0001) had significant associations with mortality. After GAM, BMI showed a significant U-shaped association with mortality (EDF = 3.2, p = 0.003). A BMI range of 31.5 ± 0.9 kg/m2 was associated with the lowest mortality.
CONCLUSION: High BMI can be a protective factor in mortality within non-elderly patients with blunt trauma. However, underweight or morbid obesity suggest a higher risk of mortality.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Blunt trauma; Generalized additive model; Obesity; Obesity paradox; Retrospective

Mesh:

Year:  2020        PMID: 33109335     DOI: 10.1016/j.amjsurg.2020.10.017

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


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