Literature DB >> 33108591

Weight Loss as the First-Line Therapy in Patients with Severe Obesity and Obstructive Sleep Apnea Syndrome: the Role of Laparoscopic Sleeve Gastrectomy.

Bilge Yılmaz Kara1, Süleyman Kalcan2, Songül Özyurt3, Aziz Gümüş3, Neslihan Özçelik3, Dilek Karadoğan3, Ünal Şahin3.   

Abstract

PURPOSE: The objective of this study is to investigate the effects of laparoscopic sleeve gastrectomy (LSG) on the polysomnographic parameters related to OSAS.
MATERIALS AND METHODS: We conducted this 3-year prospective cohort study in a tertiary care center between December 2016 and December 2019. In total, we enrolled 31 patients with severe obesity who underwent full-night polysomnography (PSG) before LSG. Later, the patients were re-evaluated by full-night PSG 12 months after the surgery.
RESULTS: The mean age of the patients was 44.1 ± 9.6 years. The mean body mass index (BMI) decreased significantly from a mean value of 49.8 ± 8.5 kg/m2 at baseline to 33.2 ± 8.2 kg/m2 and a percent BMI (%BMI) reduction of 33.8 ± 10.4% and a percent total weight loss (%TWL) of 35.4 ± 10.8% was achieved on the same day of the postsurgical PSG (p < 0.001). There was a remarkable improvement in the AHI (baseline: 36.1 ± 27.1, 12 months after the surgery: 10.3 ± 11.8; difference: 25.8 ± 22.8 events per hour) (p < 0.001). Importantly, there was a decrease in the percentage of non-rapid eye movement (NREM) 2 (p < 0.001), whereas NREM 3 and REM stages witnessed a significant increase (p = 0.001 and p < 0.001, respectively) after the surgery.
CONCLUSION: The results of this study showed that weight loss after LSG yields improvement not only in AHI but also in many polysomnographic parameters such as sleep quality and desaturation indices.

Entities:  

Keywords:  Bariatric surgery; Laparoscopic sleeve gastrectomy; Obesity; Obstructive sleep apnea; Weight loss

Mesh:

Year:  2020        PMID: 33108591     DOI: 10.1007/s11695-020-05080-4

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  3 in total

1.  [A case of obstructive sleep apnea syndrome remarkably improved by gastric restriction surgery].

Authors:  T Kurono; T Sakuma; T Shinozaki; S Kouchiyama; S Masuyama; F Kunitomo; I Kawamura; T Kuriyama
Journal:  Nihon Kyobu Shikkan Gakkai Zasshi       Date:  1990-05

2.  Long-term outcomes of laparoscopic sleeve gastrectomy - a single-center prospective observational study.

Authors:  Radu Neagoe; Mircea Muresan; Daniel Timofte; Ruxandra Darie; Ion Razvan; Septimiu Voidazan; Simona Muresan; Daniela Sala
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2019-04-08       Impact factor: 1.195

3.  Performance of Epworth Sleepiness Scale and tiredness symptom used with simplified diagnostic tests for the identification of sleep apnea.

Authors:  Eduardo Borsini; Magalí Blanco; Silvana Schonfeld; Glenda Ernst; Alejandro Salvado
Journal:  Sleep Sci       Date:  2019 Oct-Dec
  3 in total
  3 in total

Review 1.  Bariatric surgery-what the ophthalmologist needs to know.

Authors:  Tushar Hari; Samer Elsherbiny
Journal:  Eye (Lond)       Date:  2021-10-21       Impact factor: 4.456

2.  Therapeutic effect of laparoscopic sleeve gastrectomy on obstructive sleep apnea and relationship of type 2 diabetes in Japanese patients with severe obesity.

Authors:  Shingo Yanari; Akira Sasaki; Akira Umemura; Yasushi Ishigaki; Haruka Nikai; Tsuguo Nishijima; Shigeru Sakurai
Journal:  J Diabetes Investig       Date:  2022-02-08       Impact factor: 3.681

Review 3.  Obstructive Sleep Apnea and Cardiovascular Diseases: Sad Realities and Untold Truths regarding Care of Patients in 2022.

Authors:  Satya Preetham Gunta; Roopesh Sai Jakulla; Aamer Ubaid; Kareem Mohamed; Abid Bhat; Angel López-Candales; Nicholas Norgard
Journal:  Cardiovasc Ther       Date:  2022-08-11       Impact factor: 3.368

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.